Comparative Animal Mucomics: Inspiration for Functional Materials from Ubiquitous and Understudied Biopolymers.

Autor: Cerullo AR; The PhD Program in Biochemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.; The Advanced Science Research Center, Graduate Center of the City University of New York, 85 St. Nicholas Terrace, New York, New York 10031, United States.; Department of Chemistry and Biochemistry, Hunter College, 695 Park Avenue, New York, New York 10065, United States., Lai TY; The Advanced Science Research Center, Graduate Center of the City University of New York, 85 St. Nicholas Terrace, New York, New York 10031, United States., Allam B; School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, New York 11794-5000, United States., Baer A; Department of Zoology, Institute of Biology, University of Kassel, Heinrich-Plett-Strasse 40, 34132 Kassel, Germany., Barnes WJP; Centre for Cell Engineering, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, U.K., Barrientos Z; Laboratorio de Ecología Urbana, Universidad Estatal a Distancia, Mercedes de Montes de Oca, San José 474-2050, Costa Rica., Deheyn DD; Marine Biology Research Division-0202, Scripps Institute of Oceanography, UCSD, 9500 Gilman Drive, La Jolla, California 92093, United States., Fudge DS; Schmid College of Science and Technology, Chapman University, 1 University Drive, Orange, California 92866, United States., Gould J; School of Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, New South Wales 2308, Australia., Harrington MJ; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada., Holford M; The PhD Program in Biochemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.; Department of Chemistry and Biochemistry, Hunter College, 695 Park Avenue, New York, New York 10065, United States.; Department of Invertebrate Zoology, The American Museum of Natural History, New York, New York 10024, United States.; The PhD Program in Chemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.; The PhD Program in Biology, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States., Hung CS; Materials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, Ohio 45433, United States., Jain G; Schmid College of Science and Technology, Chapman University, 1 University Drive, Orange, California 92866, United States., Mayer G; Department of Zoology, Institute of Biology, University of Kassel, Heinrich-Plett-Strasse 40, 34132 Kassel, Germany., Medina M; Department of Biology, Pennsylvania State University, 208 Mueller Lab, University Park, Pennsylvania 16802, United States., Monge-Nájera J; Laboratorio de Ecología Urbana, Universidad Estatal a Distancia, Mercedes de Montes de Oca, San José 474-2050, Costa Rica., Napolitano T; The PhD Program in Biochemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.; Department of Chemistry and Biochemistry, Hunter College, 695 Park Avenue, New York, New York 10065, United States., Espinosa EP; School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, New York 11794-5000, United States., Schmidt S; Institute of Organic and Macromolecular Chemistry, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany., Thompson EM; Sars Centre for Marine Molecular Biology, Thormøhlensgt. 55, 5020 Bergen, Norway.; Department of Biological Sciences, University of Bergen, N-5006 Bergen, Norway., Braunschweig AB; The PhD Program in Biochemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.; The Advanced Science Research Center, Graduate Center of the City University of New York, 85 St. Nicholas Terrace, New York, New York 10031, United States.; Department of Chemistry and Biochemistry, Hunter College, 695 Park Avenue, New York, New York 10065, United States.; The PhD Program in Chemistry, Graduate Center of the City University of New York, 365 Fifth Avenue, New York, New York 10016, United States.
Jazyk: angličtina
Zdroj: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2020 Oct 12; Vol. 6 (10), pp. 5377-5398. Date of Electronic Publication: 2020 Sep 14.
DOI: 10.1021/acsbiomaterials.0c00713
Abstrakt: The functions of secreted animal mucuses are remarkably diverse and include lubricants, wet adhesives, protective barriers, and mineralizing agents. Although present in all animals, many open questions related to the hierarchical architectures, material properties, and genetics of mucus remain. Here, we summarize what is known about secreted mucus structure, describe the work of research groups throughout the world who are investigating various animal mucuses, and relate how these studies are revealing new mucus properties and the relationships between mucus hierarchical structure and hydrogel function. Finally, we call for a more systematic approach to studying animal mucuses so that data sets can be compared, omics-style, to address unanswered questions in the emerging field of mucomics. One major result that we anticipate from these efforts is design rules for creating new materials that are inspired by the structures and functions of animal mucuses.
Databáze: MEDLINE