Transfusion transmissible pathogens are prevalent in healthy cats eligible to become blood donors.

Autor: Mesa-Sanchez I; Animal Blood Bank, Passatge Rovira I Virgili No 9, Sabadell, 08205, Barcelona, Spain., Ferreira RRF; CECA-ICETA, University of Porto, 4050-083, Porto, Portugal.; Animal Blood Bank, Rua de João de Deus, n°741 4100-462, Porto, Portugal., Cardoso I; Animal Blood Bank, Rua de João de Deus, n°741 4100-462, Porto, Portugal., Morais M; Animal Blood Bank, Rua de João de Deus, n°741 4100-462, Porto, Portugal., Flamínio M; Animal Blood Bank, Rua de João de Deus, n°741 4100-462, Porto, Portugal., Vieira S; Animal Blood Bank, Rua de João de Deus, n°741 4100-462, Porto, Portugal., de Gopegui RR; Department of Animal Medicine and Surgery, Veterinary Faculty, Autonomous University of Barcelona, 08193, Barcelona, Spain., de Matos AJF; CECA-ICETA, University of Porto, 4050-083, Porto, Portugal.; Department of Veterinary Clinics, Institute for Biomedical Sciences of Abel Salazar, University of Porto, 4050-343, Porto, Portugal.
Jazyk: angličtina
Zdroj: The Journal of small animal practice [J Small Anim Pract] 2021 Feb; Vol. 62 (2), pp. 107-113. Date of Electronic Publication: 2020 Dec 10.
DOI: 10.1111/jsap.13257
Abstrakt: Objectives: This study aims to determine the prevalence of subclinical infectious agents considered core pathogens for worldwide screening in healthy, client-owned, indoor cats eligible to become blood donors in Spain and Portugal.
Materials and Methods: Blood samples of healthy, indoor, domestic cats selected to be potential blood donors were tested for feline leukaemia virus antigens, feline immunodeficiency virus antibodies and polymerase chain reactions for Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus Mycoplasma turicensis, feline leukaemia virus provirus, Leishmania spp. and Bartonella spp. Not all donors were tested for all agents.
Results: Overall, 5105 healthy indoor cats were tested and 8.1% (414/5105) had at least one subclinical infectious agent that is transmissible through blood product transfusion. 1.5% (77/5105) were positive for feline leukaemia virus antigens and 2.9% (148/5105) were positive for feline immunodeficiency virus antibodies, therefore they were excluded as donors. The overall prevalence of haemoplasmas in feline leukaemia virus and feline immunodeficiency virus SNAP-negative feline blood donors was 3.7% (181/4880) [1.3% (63/4880) were positive for Mycoplasma haemofelis; 2.3% (112/4880) to Candidatus Mycoplasma haemominutum and 0.12% (6/4880) to Candidatus Mycoplasma turicensis]. The prevalence of feline leukaemia provirus was 5.2% (9/173) and of Bartonella spp. was 0.2% (2/1122). None of the 173 cats were positive for Leishmania spp.
Clinical Significance: The prevalence of many transfusion transmissible pathogens was relatively high in this healthy, client-owned, indoor cats eligible to become blood donors. Performing an extended screening panel that includes at least polymerase chain reactions for Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus Mycoplasma turicensis, feline leukaemia virus provirus, and Bartonella spp., in addition to feline leukaemia virus antigens and feline immunodeficiency virus antibodies, is recommended in pet blood banks from analogous regions.
(© 2020 British Small Animal Veterinary Association.)
Databáze: MEDLINE
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