Toxicological evaluation of MnAl based permanent magnets using different in vitro models.

Autor: Rumbo C; International Research Centre in Critical Raw Materials-ICCRAM, Universidad de Burgos, Plaza Misael Bañuelos S/n, 09001, Burgos, Spain. Electronic address: crumbo@ubu.es., Espina CC; International Research Centre in Critical Raw Materials-ICCRAM, Universidad de Burgos, Plaza Misael Bañuelos S/n, 09001, Burgos, Spain., Popov VV; Israel Institute of Metals, Technion R&D Foundation Ltd., Technion City, 3200003, Haifa, Israel., Skokov K; Institute of Materials Science, Technical University of Darmstadt, Alarich-Weiss-Str. 16, D-64287, Darmstadt, Germany., Tamayo-Ramos JA; International Research Centre in Critical Raw Materials-ICCRAM, Universidad de Burgos, Plaza Misael Bañuelos S/n, 09001, Burgos, Spain. Electronic address: jatramos@ubu.es.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2021 Jan; Vol. 263, pp. 128343. Date of Electronic Publication: 2020 Sep 15.
DOI: 10.1016/j.chemosphere.2020.128343
Abstrakt: Due to economic, environmental and geopolitical issues, the development of permanent magnets with a composition free of rare earth elements and with acceptable magnetic properties has been considered a priority by the international community, being MnAl based alloys amongst the most promising candidates. The aim of this work was to evaluate the toxicity of powders of two forms of newly developed MnAl(C) permanent magnets through exposure experiments applying three model organisms, using as a benchmark powders of a commercial rare-earth-containing magnet (Nd 2 Fe 14 B). For this purpose, the direct exposure to the different particles suspensions as well as to magnets leachates was evaluated. Both viability and oxidative stress assays were applied in an adenocarcinomic human alveolar basal epithelial cell line (A549) and in the yeast Saccharomyces cerevisiae, together with the bioluminescent inhibition assay in the Gram negative bacterium Vibrio fischeri. The obtained results indicate that MnAl(C) permanent magnets, in general terms, presented similar toxicity than the Nd magnet for the selected biological models under the studied conditions. Overall, the presented data provide, for the first time, an in vitro toxicity analysis of MnAl based magnets.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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