Is Stone-free Status After Surgical Intervention for Kidney Stones Associated With Better Health-related Quality of Life? - A Multicenter Study From the North American Stone Quality of Life Consortium.

Autor: Streeper NM; Division of Urology, Penn State Milton S. Hershey Medical Center, Hershey, PA. Electronic address: nstreeper@pennstatehealth.psu.edu., Galida M; Division of Urology, Penn State Milton S. Hershey Medical Center, Hershey, PA., Boltz S; Division of Urology, Penn State Milton S. Hershey Medical Center, Hershey, PA., Li S; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Nakada SY; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Raffin EP; Department of Urology, Dartmouth Hitchcock Medical Center, Lebanon, NH., Brown DR; Department of Urology, Dartmouth Hitchcock Medical Center, Lebanon, NH., Pais VM; Department of Urology, Dartmouth Hitchcock Medical Center, Lebanon, NH., Chan JYH; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada., Scotland KB; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada., Chew BH; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada., Penniston KL; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Jazyk: angličtina
Zdroj: Urology [Urology] 2021 Feb; Vol. 148, pp. 77-82. Date of Electronic Publication: 2020 Dec 05.
DOI: 10.1016/j.urology.2020.09.058
Abstrakt: Objective: To compare the health-related quality of life (HRQOL) of patients with residual fragments after surgical intervention for kidney stones to patients that are stone-free using the disease-specific Wisconsin stone quality of life (WISQOL) questionnaire. Kidney stones contribute to impaired HRQOL, which is increasingly recognized as an important healthcare outcome measurement.
Materials and Methods: With institutional review board approval, 313 adult patients who underwent surgical intervention for kidney stones at 4 sites completed a WISQOL questionnaire. We retrospectively collected surgical data including presence of residual fragments on post-operative imaging. We calculated standardized WISQOL total and domain scores (0-100), which included items related to social functioning (D1), emotional functioning (D2), stone-related impact (D3), and vitality (D4). Scores were compared between patients with residual fragments to those who were stone-free after surgical intervention.
Results: Demographics did not differ between groups, overall mean age 54.6 ± 13.5 and 55.4% female. There was no significant difference in total WISQOL score for patients with residual fragments (n = 124) compared to patients that were stone-free (n = 189), 110.5 ± 27.8 vs 115.4 ± 23.6 respectively, (P = .12). Interestingly, patients with residual fragments who underwent secondary surgery were found to have significantly lower total WISQOL score (88.4 ± 30.1 vs 116.6 ± 25.0, P <.0001).
Conclusion: Stone-free status after surgical intervention is not associated with better HRQOL when compared with patients whose surgeries left residual fragments. Indeed, further surgical intervention on residual fragments to achieve stone-free status may actually result in worse HRQOL.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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