Autor: |
Ketharanathan B, Andersen MS, Pedersen CB, Darling P, Jakobseb J, Bechtold D, Molander LD, Gampenrieder N, Dahlrot RH, Nguyen N, Poulsen FR, Halle B; Bo.halle@rsyd.dk. |
Jazyk: |
dánština |
Zdroj: |
Ugeskrift for laeger [Ugeskr Laeger] 2020 Nov 30; Vol. 182 (49). |
Abstrakt: |
Hypoxia triggers hypoxia-inducible factor (HIF). Not only hypoxia triggers downstream HIF target genes for transcription, as intermittent hyperoxia also possesses similar capabilities, suggesting that fluctuations in oxygen availability may be equally important for inducing HIF transcription. This review describes some of the mechanisms, whereby intermittent hyperbaric hyperoxia may explain some of the observations during hyperbaric oxygen therapy such as enhanced wound healing, angiogenesis and tissue healing, and concludes that oxidative stress enhances certain antibiotics in infection control. |
Databáze: |
MEDLINE |
Externí odkaz: |
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