Epidemiological Characteristics of Corneal Donors at a Tertiary Referral Center in Turkey: An Eye Bank Study.

Autor: Tanyildiz B; From the University of Health Sciences, Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Ophthalmology, Istanbul, Turkey., Göktaş E, Tutaş Günaydın N, Zorlutuna Kaymak N, Kanar HS, Kandemir B
Jazyk: angličtina
Zdroj: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [Exp Clin Transplant] 2021 Apr; Vol. 19 (4), pp. 367-373. Date of Electronic Publication: 2020 Nov 27.
DOI: 10.6002/ect.2020.0310
Abstrakt: Objectives: The aim of this study was to evaluate the demographic features of corneal donors and available data of corneas in our eye bank during a 14-year period.
Materials and Methods: The demographic features of the corneal donors, the causes of death, the death-to-excision interval, serology results, the mean endothelial cell density, and the reasons for discarding the corneas were retrospectively evaluated.
Results: During the study period, 6524 corneas were retrieved from 3326 donors (76.1% male, 23.9% female). Mean donor age was 43.7 ± 16.0 years (range, 4-75 years; median 45.0 years). The most common cause of death was cardiovascular disease (n = 1467; 44.1%). The most common reason for discarding corneas was positive serology (n = 509; 78.6%). The mean endothelial cell density was 3030.1 ± 484.3 cells/mm². There was a weak negative statistically significant correlation between age and endothelial cell density (Pearson correlation coefficient r = -0.187, P < .001). Multiorgan donations made up 1.5% of the whole group (n = 50).
Conclusions: We believe that preoperative detailed evaluations of graft quality in addition to review of donor-related medical records and data from previous surgeries, after collecting them in a single system, will have a positive effect on postoperative corneal survival.
Databáze: MEDLINE