Outcome of Patients Admitted to Intensive Care Units due to Influenza-Related Severe Acute Respiratory Illness in 2017-2018 Flu Season: A Multicenter Study from Turkey.

Autor: Ortac Ersoy E; Division of Intensive Care Medicine, Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey, ebru.ortac@hacettepe.edu.tr., Er B; Division of Intensive Care Medicine, Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey., Ciftci F; Department of Chest Diseases, Intensive Care Unit, Ankara University Faculty of Medicine, Ankara, Turkey., Gulleroglu A; Intensive Care Unit, Baskent University, Ankara, Turkey., Suner K; Intensive Care Unit, Sakarya University Education and Research Hospital, Sakarya, Turkey., Arpinar B; Intensive Care Unit, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey., Aygencel G; Medical Intensive Care Unit, Gazi University Faculty of Medicine, Ankara, Turkey., Bacakoglu F; Division of Chest Diseases, Intensive Care Unit, Ege University Faculty of Medicine, İzmir, Turkey., Akpinar S; Medical Intensive Care Unit, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey., Comert B; Medical Intensive Care Unit, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey., Sungurtekin H; Intensive Care Unit, Pamukkale University Faculty of Medicine, Denizli, Turkey., Altıntas D; Medical Intensive Care Unit, Ankara University Faculty of Medicine, Ankara, Turkey., Rollas K; Intensive Care Unit, Tepecik Education Hospital, University of Health Sciences, Izmir, Turkey., Turan S; Intensive Care Unit, Ankara City Hospital, University of Health Sciences, Ankara, Turkey., Topeli A; Division of Intensive Care Medicine, Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Respiration; international review of thoracic diseases [Respiration] 2020; Vol. 99 (11), pp. 954-960. Date of Electronic Publication: 2020 Dec 03.
DOI: 10.1159/000511092
Abstrakt: Background: Influenza can cause severe acute respiratory illness (SARI), which occurs as local outbreaks or seasonal epidemics with high intensive care unit (ICU) admission and mortality rates. Mortality is mainly due to SARI.
Objective: The aim of this study was to evaluate the outcome of patients admitted to ICU due to influenza-related SARI in 2017-2018 flu season in Turkey.
Methods: A retrospective multicenter study was conducted in 13 ICUs with a total of 216 beds from 6 cities in Turkey. All adult patients (over 18 years) admitted to the ICUs in 2017-2018 flu season (between September 1, 2017, and April 30, 2018) because of SARI and with a positive nasopharyngeal swab for influenza were included in the study.
Results: A total of 123 cases were included in the study. The mean age of patients was 64.5 ± 17.5 years, and 66 (53.7%) patients were older than 65 years. The ICU mortality was 33.9%, and hospital mortality was 35.6%. Invasive mechanical ventilation (IMV), acute kidney injury (AKI), hematologic malignancy, and >65 years of age were the factors affecting mortality in influenza.
Conclusion: SARI due to influenza carries a high mortality rate, and IMV, AKI, presence of hematologic malignancy, and older age are independent risk factors for mortality.
(© 2020 S. Karger AG, Basel.)
Databáze: MEDLINE