Effect of dynamic position changes on adenoma detection rate during colonoscope withdrawal: systematic review and meta-analysis.

Autor: Nutalapati V; Department of Gastroenterology, University of Kansas Medical Center, Kansas City, Kansa, United States., Desai M; Department of Gastroenterology, Kansas City Veterans Medical Center, Kansas City, Kansas, United States., Thoguluva-Chandrasekar VS; Department of Gastroenterology, University of Kansas Medical Center, Kansas City, Kansa, United States., Olyaee M; Department of Gastroenterology, University of Kansas Medical Center, Kansas City, Kansa, United States., Rastogi A; Department of Gastroenterology, University of Kansas Medical Center, Kansas City, Kansa, United States.
Jazyk: angličtina
Zdroj: Endoscopy international open [Endosc Int Open] 2020 Dec; Vol. 8 (12), pp. E1842-E1849. Date of Electronic Publication: 2020 Nov 17.
DOI: 10.1055/a-1265-6634
Abstrakt: Background and study aims  The adenoma detection rate (ADR) is an important quality metric of colonoscopy. Higher ADR correlates with lower incidence of interval colorectal cancer. ADR is variable between endoscopists and depends upon the withdrawal technique amongst other factors. Dynamic position change (lateral rotation of patients with a view to keep the portion of the colon being inspected at a higher level) helps with luminal distension during the withdrawal phase. However, impact of this on ADR is not known in a pooled sample. We performed a systematic review and meta-analysis to study the impact of dynamic position changes during withdrawal phase of colonoscopy on ADR Methods  A comprehensive search of MEDLINE, EMBASE, Google Scholar, and the Cochrane Database was conducted from each database's inception to search for studies comparing dynamic position changes during colonoscope withdrawal with static left lateral position (control). The primary outcome of interest was ADR. Other studied outcomes were polyp detection rate (PDR) and withdrawal time. Outcomes were reported as pooled odds ratio (OR) with 95 % confidence intervals (CI) with statistical significance ( P  < 0.05). RevMan 5.3 software was used for statistical analysis. Results  Six studies were included in our analysis with 2860 patients. Of these, dynamic position change was implemented in 1177 patients while 1183 patients served as the controls. ADR was significantly higher in the dynamic position change group with pooled OR 1.36 (95 % CI, 1.15-1.61; P  < 0.01). There was low heterogeneity in inclusion studies (I 2  = 0 %). PDR was numerically higher in position change group (53.4 % vs 49.6 %) but not statistically significant ( P  = 0.16). Mean withdrawal time did not significantly change with dynamic position change (12.43 min vs 11.46 min, P  = 0.27). Conclusion  Position change during the withdrawal phase of colonoscopy can increase the ADR compared to static left lateral position. This is an easy and practical technique that can be implemented to improve ADR.
Competing Interests: Competing interests The authors declare that they have no conflict of interest.
(The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
Databáze: MEDLINE
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