Application of 18 F-FDG PET/CT in evaluation of curative effect and prognosis for small cell lung cancer.

Autor: Xu P; PET/CT Center, Second Xiangya Hospital, Central South University, Changsha 410011, China. 739144105@qq.com., Wang Y; PET/CT Center, Second Xiangya Hospital, Central South University, Changsha 410011, China. 13973186448@163.com.
Jazyk: English; Chinese
Zdroj: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences [Zhong Nan Da Xue Xue Bao Yi Xue Ban] 2020 Oct 28; Vol. 45 (10), pp. 1255-1260.
DOI: 10.11817/j.issn.1672-7347.2020.190151
Abstrakt: Small cell lung cancer belongs to neuroendocrine tumors and is the most malignant one in lung cancer. It possesses clinical features such as rapid growth, easy early metastasis, and poor prognosis. PET/CT is a molecular imaging technique that combines morphological and metabolic imaging. It has been widely used in the diagnosis, staging, treatment planning, efficacy and prognosis evaluation of tumors. This article reviews the efficacy, prognostic parameters, evaluation criteria, possible influencial factors, clinical application and value of 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/CT in small cell lung cancer. The accuracy and sensitivity of 18 F-FDG PET/CT in small cell lung cancer stage, efficacy and prognosis evaluation are significantly higher than those of traditional imaging methods. Maximal standardized uptake, metabolic tumor volume, and total lesion glycolysis have been applied in efficacy and prognosis prediction, which have important value in developing the personalized treatment and improving the survival for small cell lung cancer patient.
Databáze: MEDLINE