Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a case report and review of the literature.

Autor: Martín-Pérez JA; Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Ejército Constitucionalista, Chinam Pac de Juárez, Calz. Ignacio Zaragoza 1711, 09220, Mexico City, MX, Mexico. chucho0892@gmail.com.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico. chucho0892@gmail.com., Torres-Silva C; Oncology Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., Tenorio-Arguelles R; Oncology Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., García-Corona DA; Oncology Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., Silva-González S; Oncology Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., Dominguez-Rodriguez JA; Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Ejército Constitucionalista, Chinam Pac de Juárez, Calz. Ignacio Zaragoza 1711, 09220, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., De Alba-Cruz I; Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Ejército Constitucionalista, Chinam Pac de Juárez, Calz. Ignacio Zaragoza 1711, 09220, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., Nagore-Ancona JF; Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Ejército Constitucionalista, Chinam Pac de Juárez, Calz. Ignacio Zaragoza 1711, 09220, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., González-Luna JA; Surgical Department, 'General Ignacio Zaragoza' Regional Hospital, Ejército Constitucionalista, Chinam Pac de Juárez, Calz. Ignacio Zaragoza 1711, 09220, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico., López-Bochm KA; Pathology Department, 'General Ignacio Zaragoza' Regional Hospital, Mexico City, MX, Mexico.; Social Services and Security Institute for the State Employees (I.S.S.S.T.E.), Mexico City, MX, Mexico.
Jazyk: angličtina
Zdroj: Journal of medical case reports [J Med Case Rep] 2020 Dec 02; Vol. 14 (1), pp. 234. Date of Electronic Publication: 2020 Dec 02.
DOI: 10.1186/s13256-020-02576-6
Abstrakt: Background: Gastric carcinoma (GC) with second primary malignancy (SPM) is the most frequent combination within the multiple primary malignancies (MPM) group. The presentation of a GC associated with a synchronized SPM in the kidney is extremely rare and unusual. This study presents a rare case of synchronous tumors, describes the main associated risk factors, and emphasizes the need to rule out SPM.
Main Body: We present the case of a 63-year-old Hispanic woman with a history of smoking, weight loss, and gastrointestinal (GI) bleeding. GC was diagnosed by endoscopy, and during her workup for metastatic disease, a synchronous SPM was noted in the left kidney. The patient underwent resection of both tumors with a satisfactory postoperative course. A systematic review of the literature was performed using the Medline/PubMed, Science Direct, Scopus, and Google Scholar databases. A search of the literature yielded 13 relevant articles, in which the following main risk factors were reported: the treatment utilized, the grade and clinical stage, histopathological report, and in some cases survival. It is concluded that advanced age (> 60 years) and smoking are the main associated risk factors.
Conclusion: Gastric carcinoma is the second most frequent neoplasm of the GI tract and the main neoplasm that presents a SPM. MPM screening is recommended in patients with gastric cancer. The clinical discovery of MPM of renal origin is rare and hence the importance of the current report.
Databáze: MEDLINE
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