Outcomes of drug-induced acute pancreatitis: a ten-year experience of an academic center.

Autor:	Sánchez-Aldehuelo R; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal, España., García García de Paredes A; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal, España., Rojo Lázaro D; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal., Martínez Ortega A; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal., García de la Filia Molina I; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal., López-Durán S; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal, España., Rodríguez-Gandía MÁ; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal, España., López-Sanromán A; Digestive Diseases and Hepatology Service, Hospital Universitario Ramón y Cajal., Albillos A; Digestive Diseases and Hepatology , Hospital Universitario Ramón y Cajal.
Jazyk:	angličtina
Zdroj:	Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva [Rev Esp Enferm Dig] 2021 Apr; Vol. 113 (4), pp. 276-279.
DOI:	10.17235/reed.2020.7443/2020
Abstrakt:	Background: drug-induced pancreatitis is an unexplored entity. Methods: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed. Results: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %. Conclusion: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.
Databáze:	MEDLINE
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