Nanoencapsulated fluoride as a remineralization option for dental erosion: an in vitro study.

Autor: de Lavôr JR; Morphology Department, Federal University of Paraíba, João Pessoa, Brazil., Fernandes NLS; Morphology Department, Federal University of Paraíba, João Pessoa, Brazil., de Sousa EBG; Morphology Department, Federal University of Paraíba, João Pessoa, Brazil., da Cunha JL; Morphology Department, Federal University of Paraíba, João Pessoa, Brazil., Meira IA; Graduate Program of Dentistry Clinic, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil., Correia Sampaio F; Morphology Department, Federal University of Paraíba, João Pessoa, Brazil., de Oliveira AFB; Clinical and Social Dentistry Department, Federal University of Paraíba, João Pessoa, Brazil.
Jazyk: angličtina
Zdroj: Acta odontologica Scandinavica [Acta Odontol Scand] 2021 Jul; Vol. 79 (5), pp. 321-326. Date of Electronic Publication: 2020 Nov 27.
DOI: 10.1080/00016357.2020.1849793
Abstrakt: Objective: To compare the in vitro performance of different dentifrices indicated for dental erosion and a new dentifrice with controlled fluoride release system (NanoF) in terms of surface microhardness remineralization in enamel erosion lesions.
Materials and Methods: 72 human enamel specimens were divided into 6 groups ( n  = 12): PC (100% NaF - positive control); NC (Placebo - negative control); 50%nF (50% NanoF + 50% free NaF), 100%nF (100% NanoF); PN (Sensodyne ® ProNamel™) and AG (Colgate ® Sensitive Pro-Relief™). A surface microhardness analysis was performed before (SH 0 ) and after (SH 1 ) the erosion lesion formation. The blocks were submitted to a 5-day de-remineralization cycling model, consisting of 90 s immersion on 0.1% citric acid (4x/day) and 1 min treatment with dentifrice slurries along with 1 mL/block of human saliva (2x/day). Lastly, the final surface microhardness analysis (SH 2 ) was measured and the percentage of surface microhardness remineralization (%SMH R ) was calculated. Data were analysed with 2-way ANOVA and Tukey's test ( p  < .05).
Results: Statistically significant differences were observed for SH 2 and %SMH R between NC and AG with the other groups ( p  < .05). The best %SMH R from the experimental groups was found in 100%nF and PN.
Conclusion: Dentifrices with NanoF exhibited a surface microhardness remineralization similar to sodium fluoride (PC). Therefore, NanoF dentifrice can be an alternative to prevent and treat patients with dental erosion.
Databáze: MEDLINE
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