| Autor: |
Schwartz JC; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA., Snyder EM; Geneticure, Inc., Rochester, MN, USA., Olson TP; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA., Johnson BD; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA., Wheatley-Guy CM; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of sports sciences [J Sports Sci] 2021 May; Vol. 39 (9), pp. 961-968. Date of Electronic Publication: 2020 Nov 26. |
| DOI: |
10.1080/02640414.2020.1851927 |
| Abstrakt: |
Inadequate hyperventilation and inefficient alveolar to arterial gas exchange are gas exchange challenges that can limit capacity and cause exercise-induced arterial hypoxaemia (EIAH). This work evaluated if the prevalence of gas exchange inefficiencies, defined as AaDO 2 >25 mmHg, PaCO 2 >38 mmHg, and/or ΔPaO 2 >-10 mmHg at any point during constant-load exercise in healthy, active, but not highly trained, individuals suggested an innate sex difference that would make females more susceptible to EIAH. Sixty-four healthy, active males and females completed 18-min of cycling exercise (moderate and vigorous intensity, 9 min/stage). Arterial blood gases were measured at rest and every 3-min during exercise, while constantly assessing gas exchange. Both sexes demonstrated similar levels of AaDO 2 widening until the final 3 min of vigorous exercise, where females demonstrated a trend for greater widening than males (16.3±6.2 mmHg vs. 19.1±6.0 mmHg, p=0.07). Males demonstrated a blunted ventilatory response to moderate exercise with higher PaCO 2 (38.5±2.6 vs. 36.5±2.4, p=0.002) and a lower ventilation when corrected for workload (0.42±0.1 vs. 0.48±0.1, p=0.002). No significant arterial hypoxaemia occurred, but in 6 M and 5 F SaO 2 dropped by ≥2%. There was no difference in prevalence of pulmonary gas exchange inefficiencies between sexes, but the type of inefficiency was influenced by sex. Abbreviations: AaDO 2 : alveolar-arterial oxygen difference; BP: blood pressure; EIAH: exercise-induced arterial hypoxaemia; F: females; HR: heart rate; M: males; Q: cardiac output; PaCO 2 : arterial partial pressure of carbon dioxide; PaO 2 : arterial partial pressure of oxygen; ΔPaO 2 : change in arterial partial pressure of oxygen; PAO 2 : alveolar partial pressure of oxygen; RPE: rating of perceived exertion; SaO 2 : arterial oxygen saturation; V E : ventilation; V E /VCO 2 : ventilatory equivalent for carbon dioxide; VO 2PEAK : peak oxygen consumption; W MAX : workload maximum. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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