A Very Rare Type of Leukemia in a Young Pediatric Patient Treated With Hematopoietic Stem Cell Transplantation: Blastic Plasmacytoid Dendritic Cell Neoplasm.
| Autor: | Tekkeşin F; Departments of Pediatric Hematology and Oncology., Asarcikli F; Departments of Pediatric Hematology and Oncology., Yildirim ÜM; Departments of Pediatric Hematology and Oncology., Zemheri IE; Pathology, SBU Ümraniye Training and Research Hospital, İstanbul, Turkey., Kiliç SÇ; Departments of Pediatric Hematology and Oncology. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2021 Mar 01; Vol. 43 (2), pp. e288-e291. |
| DOI: | 10.1097/MPH.0000000000001999 |
| Abstrakt: | Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a newly identified, very rare, highly aggressive hematopoietic neoplasm, primarily found in elderly males. They typically present in the form of skin involvement with a high frequency of lymph node and bone marrow involvement. BPDCN has a very poor prognosis, with no consensus on a widely accepted treatment modality. Here we present a very young patient with BPDCN, who presented with generalized lymphadenopathy, skin involvement, and leukemic blasts in the bone marrow. She was treated with high-risk acute lymphocytic leukemia protocol, followed by allogeneic hematopoietic stem-cell transplantation, and has been in clinical remission for 12 months. Competing Interests: The authors declare no conflict of interest. (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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