| Autor: |
Tassi PG; Department of Obstetrics and Gynecology, University of Brescia, Italy., Tarantini M, Cadenelli GP, Gastaldi A, Benedetti M |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of clinical pharmacology, therapy, and toxicology [Int J Clin Pharmacol Ther Toxicol] 1987 Oct; Vol. 25 (10), pp. 582-8. |
| Abstrakt: |
The efficacy of two randomized antibiotic prophylactic schedules with ceftazidime (group A: single preoperative 2 g intramuscular dose; group B: 3 perioperative 1 g intramuscular doses every 6 h) was evaluated in 200 pregnant women undergoing cesarean section. Postoperative complications were observed in 9 cases (4 in group A and 5 in group B; p = NS). Analysis of possible risk factors revealed 1) a relationship between postoperative morbidity and overweight (body mass index above 30) in group A only; 2) a possible contributory effect of duration of labor (more than 6 h) in group A; and 3) a possible effect of duration of rupture of the membranes (more than 6 h) in group B only. The results obtained lead to the conclusion that single-dose prophylaxis with ceftazidime is as effective as short-term 3-dose ceftazidime prophylaxis in preventing post-cesarean complications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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