HIV-1 infection of the kidney: mechanisms and implications.

Autor:	Hughes K; Division of Infectious Diseases, Department of Medicine.; Duke Human Vaccine Institute., Chang J; Division of Infectious Diseases, Department of Medicine.; Duke Human Vaccine Institute., Stadtler H; Division of Infectious Diseases, Department of Medicine.; Duke Human Vaccine Institute., Wyatt C; Division of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Klotman M; Division of Infectious Diseases, Department of Medicine.; Duke Human Vaccine Institute., Blasi M; Division of Infectious Diseases, Department of Medicine.; Duke Human Vaccine Institute.
Jazyk:	angličtina
Zdroj:	AIDS (London, England) [AIDS] 2021 Mar 01; Vol. 35 (3), pp. 359-367.
DOI:	10.1097/QAD.0000000000002753
Abstrakt:	People living with HIV are at higher risk for acute and chronic kidney disease compared with uninfected individuals. Kidney disease in this population is multifactorial, with several contributors including HIV infection of kidney cells, chronic inflammation, genetic predisposition, aging, comorbidities, and coinfections. In this review, we provide a summary of recent advancements in the understanding of the mechanisms and implications of HIV infection and kidney disease, with particular focus on the role of direct HIV infection of renal cells. (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu