Moderate and severe periodontitis are positively associated with metabolic syndrome.

Autor: Gomes-Filho IS; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil. isuzart@gmail.com., Balinha IDSCE; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., da Cruz SS; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil.; Health Sciences Center, Federal University of Recôncavo of Bahia, Santo Antônio de Jesus, Bahia, Brazil., Trindade SC; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Cerqueira EMM; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Passos-Soares JS; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil.; Department of Preventive Dentistry, Federal University of Bahia, Salvador, Bahia, Brazil., Coelho JMF; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Ladeia AMT; Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, Salvador, Bahia, Brazil., Vianna MIP; Department of Preventive Dentistry, Federal University of Bahia, Salvador, Bahia, Brazil., Hintz AM; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., de Santana TC; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Dos Santos PP; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Figueiredo ACMG; Department of Public Health of Federal District, Brasília, Distrito Federal, Brazil., da Silva ICO; Department of Health, Feira de Santana State University, Avenida Getúlio Vargas, 379, Centro, Feira de Santana, Bahia, 44025-010, Brazil., Scannapieco FA; Department of Oral Biology, University of Buffalo, Buffalo, NY, USA., Barreto ML; Collective Health Institute, Federal University of Bahia, Salvador, Bahia, Brazil., Loomer PM; School of Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Jazyk: angličtina
Zdroj: Clinical oral investigations [Clin Oral Investig] 2021 Jun; Vol. 25 (6), pp. 3719-3727. Date of Electronic Publication: 2020 Nov 23.
DOI: 10.1007/s00784-020-03699-2
Abstrakt: Objective: This study investigated the association between periodontitis severity (exposure) and metabolic syndrome (MetS - outcome), using two criteria for diagnosis of the outcome, since this relationship remains unexplored.
Materials and Methods: A case-control study was conducted with 870 individuals: 408 with first MetS diagnosis (cases) and 462 without MetS (controls). Participants' general information was obtained using a questionnaire and laboratory data was collected from medical records. Periodontitis severity criteria followed the Center for Disease Control and Prevention: none, mild, moderate, and severe. Odds ratios (OR) and 95% confidence intervals (95% CI) were determined by logistic regression analysis.
Results: Findings showed a positive association between moderate and severe periodontitis and MetS: OR adjusted = 1.64 (95% CI: 1.01 to 2.68) and OR adjusted = 1.94 (95% CI: 1.19 to 3.16), respectively, after adjustment for age, sex, schooling level, smoking habit, and cardiovascular disease. The adjusted measurements showed that among individuals with moderate or severe periodontitis, the probability of having MetS was around two times greater than among those without periodontitis, and that the chance was greater among participants with severe periodontitis than those with moderate periodontitis.
Conclusion: An association between the severity of periodontal status and MetS was found, suggesting a possible relationship between the two diseases.
Clinical Relevance: MetS influences the etiology of cardiovascular diseases, one of the leading causes of mortality worldwide. The findings suggest that the greater the severity of periodontitis, the greater is the association magnitude with MetS. The health professional needs to recognize that the importance of periodontal disease may play in MetS.
Databáze: MEDLINE
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