Phytosynthesized nanoparticles as a potential cancer therapeutic agent.

Autor: Jeevanandam J; CQM - Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal., Kulabhusan PK; Department of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, ON K1N6N5 Canada., Sabbih G; Chemical Engineering Department, University of Tennessee, Chattanooga, TN 37403 USA., Akram M; Department of Eastern Medicine, Government College University, Faisalabad, 38000 Pakistan., Danquah MK; Chemical Engineering Department, University of Tennessee, Chattanooga, TN 37403 USA.
Jazyk: angličtina
Zdroj: 3 Biotech [3 Biotech] 2020 Dec; Vol. 10 (12), pp. 535. Date of Electronic Publication: 2020 Nov 16.
DOI: 10.1007/s13205-020-02516-7
Abstrakt: Plants are the well-known sources for the hyper-accumulation and reduction of metallic ions. Analysis of various plant extracts has justified the presence of different types of phytochemicals that possess the stabilization and reduction functionalities of precursors to form nanoparticles. Such characteristics make plants as an attractive source for synthesizing eco-friendly nanoparticles (NPs) with potentially less toxicity to the body. Recently, phytosynthesized nanoparticles have been explored for targeted inhibition and diagnosis of cancer cells without affecting non-cancerous healthy cells. The aim of this review is to discuss the characteristic performance of NPs synthesized from various plant sources for the diagnosis and inhibition of cancer. The mode of action of phytosynthesized nanoparticles for anti-cancer applications are also discussed.
Competing Interests: Conflict of interestThe authors declare that they have no conflict of interest.
(© King Abdulaziz City for Science and Technology 2020.)
Databáze: MEDLINE
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