Smoking has a dose-dependent effect on the incidence of preoperative opioid consumption in female geriatric patients with spine disease.
Autor: | Christian ZK; UT Southwestern Medical Center, Department of Neurological Surgery, United States., Youssef CA; UT Southwestern Medical Center, Department of Neurological Surgery, United States., Aoun SG; UT Southwestern Medical Center, Department of Neurological Surgery, United States; UT Southwestern Spine Center, United States. Electronic address: salahaoun@hotmail.com., Afuwape O; UT Southwestern Medical Center, Department of Neurological Surgery, United States., Barrie U; UT Southwestern Medical Center, Department of Neurological Surgery, United States., Johnson ZD; UT Southwestern Medical Center, Department of Neurological Surgery, United States., El Ahmadieh TY; UT Southwestern Medical Center, Department of Neurological Surgery, United States., Hall K; UT Southwestern Medical Center, Department of Neurological Surgery, United States; UT Southwestern Spine Center, United States., Peinado Reyes V; UT Southwestern Medical Center, Department of Neurological Surgery, United States; UT Southwestern Spine Center, United States., Wingfield SA; UT Southwestern Medical Center, Department of Internal Medicine, Division of Geriatric Medicine, United States., Bagley CA; UT Southwestern Medical Center, Department of Neurological Surgery, United States; UT Southwestern Medical Center, Department of Orthopedic Surgery, United States; UT Southwestern Spine Center, United States. |
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Jazyk: | angličtina |
Zdroj: | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2020 Nov; Vol. 81, pp. 173-177. Date of Electronic Publication: 2020 Oct 10. |
DOI: | 10.1016/j.jocn.2020.09.066 |
Abstrakt: | Tobacco use and narcotic medication have been associated with worse functional outcomes after surgery. Our goal was to investigate potential associations between smoking and preoperative opioid consumption in a geriatric population undergoing spine surgery, and their impact on postoperative outcomes. The records of 536 consecutive patients aged more than 65 years who underwent elective spinal surgery between November 2014 and August 2017 at a single institution were reviewed. Primary outcomes included rates of preoperative opioid consumption and postoperative hospital length of stay and complications. Males were more likely to be smokers than females (p < 0.001), whereas females were more likely to take opioid analgesics preoperatively (p = 0.022). Women with a history of smoking were more likely to have increased preoperative opioid consumption compared to those with no history of smoking (63.64% vs. 42.04%; p < 0.001). Such a relationship was not found in men. Subgroups analysis of female patients with a history of tobacco use comparing current and former smoker status showed that both groups exhibited increased preoperative opioid consumption compared to patients who never smoked (88.89% vs 42.04%; p < 0.001 for current users; 59.42% vs 42.04% for former users; p = 0.008). There was also a dose-depended relationship between smoking and increased preoperative opioid consumption. Geriatric female spine patients with a history of smoking have a higher incidence of preoperative opioid consumption. Opioid intake appears to increase with the number of pack-years, both in patients with a history of smoking and in those who currently smoke. (Copyright © 2020 Elsevier Ltd. All rights reserved.) |
Databáze: | MEDLINE |
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