| Autor: |
Odusina BO; Department of Chemical Sciences, Tai Solarin University of Education, Ijebu Ode, Ogun State, Nigeria., Onocha PA; Department of Chemistry, University of Ibadan, Ibadan, Nigeria. |
| Jazyk: |
angličtina |
| Zdroj: |
Natural product research [Nat Prod Res] 2022 Apr; Vol. 36 (8), pp. 2154-2157. Date of Electronic Publication: 2020 Nov 23. |
| DOI: |
10.1080/14786419.2020.1844691 |
| Abstrakt: |
Physalis angulata is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of Physalis angulata was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various spectroscopic techniques. A new compound named as Squalen-1-ol, Phytol, squalene and α-tocopherol were isolated. These compounds were isolated for the first time from Physalis angulata. The extract of Physalis angulata gave a significant IC 50 value of 0.77 mg/mL as compared with the standard ascorbic acid with IC 50 value of 0.24 mg/mL. It can be correlated that the antioxidant activity of Physalis angulata could be attributed to the presence of α - tocopherol which is a known antioxidant. The presence of these compounds gives a further added pharmacological value to the plant. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
