Effect of radiofrequency on patellar ligament repair of Wistar rats.

Autor: Pinheiro NM; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Cardoso FAG; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Mendonça AC; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Zanier-Gomes PH; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Corrêa RRM; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Carneiro ACDM; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil., Crema VO; Structural Biology Department, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil. Electronic address: virginia.crema@uftm.edu.br.
Jazyk: angličtina
Zdroj: Journal of bodywork and movement therapies [J Bodyw Mov Ther] 2020 Oct; Vol. 24 (4), pp. 164-167. Date of Electronic Publication: 2020 Jul 30.
DOI: 10.1016/j.jbmt.2020.07.012
Abstrakt: This study aimed to evaluate the effects of radiofrequency (RF) on patellar ligament repair through the analysis of type I and III collagens and immunostaining for TGF-β3. To evaluate the effect of RF on patellar ligament repair of Wistar rats, cross-sectional incision (60% of the width - grade I) was performed in patellar ligaments of the groups: lesion (L, n = 7), treated with RF on the 5-day (5RF, n = 7) and 7-day (7RF, n = 7) post injury were compared to control group (C, n = 7). Histological evaluation, immunohistochemistry, morphometry and statistical analysis were performed. At 10 days post injury, ligament rupture were observed only in L. Active fibroblasts, type 3 collagen and TGF-β3 in L, 5RF and 7RF was significantly (p < 0.05) higher than control (C). Type 1 collagen was significantly (p < 0.05) higher in C than L, 5RF and 7RF. A positive correlation (p < 0.05) was observed: TGF-β3 vs active fibroblasts and TGF-β3 vs type 3 collagen; otherwise, negative correlation (p < 0.05): type I collagen vs TGF-β3. These results suggest that RF seemed to accelerate the wound healing process of the patellar ligament and may be used as a non-invasive treatment of partial ligament injuries.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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