Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations.

Autor:	Sikkes SAM; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands., Tang Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Disorders, Beijing, China., Jutten RJ; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands., Wesselman LMP; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands., Turkstra LS; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada., Brodaty H; Centre for Healthy Brain Ageing and Dementia Centre for Research Collaboration, School of Psychiatry, UNSW, Sydney, Australia., Clare L; Centre for Research in Ageing and Cognitive Health, College of Medicine and Health, University of Exeter, Exeter, UK., Cassidy-Eagle E; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA., Cox KL; Medical School, University of Western Australia, Perth, Western Australia, Australia., Chételat G; Normandie Univ, UNICAEN, INSERM, U1237, PhIND 'Physiopathology and Imaging of Neurological Disorders,', Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France., Dautricourt S; Normandie Univ, UNICAEN, INSERM, U1237, PhIND 'Physiopathology and Imaging of Neurological Disorders,', Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France., Dhana K; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA., Dodge H; Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA.; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA., Dröes RM; Department of Psychiatry, Amsterdam University Medical Center, VUmc, Amsterdam, the Netherlands., Hampstead BM; Department of Psychiatry, University of Michigan and VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA., Holland T; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA., Lampit A; Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia., Laver K; Department of Rehabilitation, Aged and Extended Care, College of Medicine and Public Health, Flinders University, Adelaide, Australia., Lutz A; Lyon Neuroscience Research Center INSERM U1028, CNRS UMR5292, Lyon University, Lyon, France., Lautenschlager NT; Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia.; NorthWestern Mental Health, Melbourne Health, Melbourne, Australia., McCurry SM; Department of Child, Family, and Population Health Nursing, University of Washington, Seattle, Washington, USA., Meiland FJM; Department of Psychiatry, Amsterdam University Medical Center, VUmc, Amsterdam, the Netherlands., Morris MC; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA., Mueller KD; Wisconsin Alzheimer's Institute, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA., Peters R; Department of Psychology, University of New South Wales, Randwick, Sydney, Australia.; Neuroscience Research Australia, Sydney, Australia., Ridel G; The University of East Anglia, Norwich, UK., Spector A; Department of Clinical, Educational & Health Psychology, University College London, London, UK., van der Steen JT; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.; Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, the Netherlands., Tamplin J; Faculty of Fine Arts and Music, University of Melbourne, Melbourne, Victoria, Australia., Thompson Z; Faculty of Fine Arts and Music, University of Melbourne, Melbourne, Victoria, Australia., Bahar-Fuchs A; Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia.; Centre for Research on Ageing, Health, and Wellbeing, Research School of Population Health, The Australian National University, Canberra, Australia.
Jazyk:	angličtina
Zdroj:	Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2021 Feb; Vol. 17 (2), pp. 255-270. Date of Electronic Publication: 2020 Nov 20.
DOI:	10.1002/alz.12188
Abstrakt:	Introduction: Non-pharmacological treatments (NPTs) have the potential to improve meaningful outcomes for older people at risk of, or living with dementia, but research often lacks methodological rigor and continues to produce mixed results. Methods: In the current position paper, experts in NPT research have specified treatment targets, aims, and ingredients using an umbrella framework, the Rehabilitation Treatment Specification System. Results: Experts provided a snapshot and an authoritative summary of the evidence for different NPTs based on the best synthesis efforts, identified main gaps in knowledge and relevant barriers, and provided directions for future research. Experts in trial methodology provide best practice principles and recommendations for those working in this area, underscoring the importance of prespecified protocols. Discussion: We conclude that the evidence strongly supports various NPTs in relation to their primary targets, and discuss opportunities and challenges associated with a unifying theoretical framework to guide future efforts in this area. (© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)
Databáze:	MEDLINE
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