Impact of the First Wave of COVID-19 on Pediatric Oncology and Hematology: A Report from the French Society of Pediatric Oncology.

Autor: Rouger-Gaudichon J; Department of Pediatric Oncology and Hematology, University Hospital of Caen (CHU Caen), 14000 Caen, France., Thébault E; Department of Oncology for Child and Adolescent, Gustave Roussy, 94800 Villejuif, France., Félix A; Department of Oncology for Child and Adolescent, Gustave Roussy, 94800 Villejuif, France., Phulpin A; Department of Pediatric Oncology and Hematology, University Hospital of Nancy (CHRU Nancy), 54000 Nancy, France., Paillard C; Department of Pediatric Hematology and Oncology, Hôpital Hautepierre, 67200 Strasbourg, France., Alimi A; Department of Pediatric, Adolescent, Young Adult, Institut Curie, CEDEX 05, 75248 Paris, France., Brethon B; Department of Pediatric Hematology, Robert Debre Hospital, APHP, 75019 Paris, France., Gouache E; Department of Pediatric Hemato-Oncology, Hospital Armand Trousseau, 75012 Paris, France., Raimbault S; Pediatric Oncology Unit, Centre Oscar Lambret, 59000 Lille, France., de Berranger E; Department of Pediatric Hematology, University Hospital of Lille (CHU Lille), 59000 Lille, France., Poirée M; Department of Pediatric Oncology and Hematology, University Hospital of Nice, 06000 Nice, France., Bouttefroy S; Institute of Pediatric Hematology and Oncology IHOPE, Centre Leon Berard, Hospices Civils de Lyon, 69002 Lyon, France., André N; Department of Pediatric Hematology and Oncology, Hôpital pour enfant de La Timone, AP-HM, 13005 Marseille, France., Gandemer V; Department of Paediatric Hemato-Oncology, University Hospital of Rennes, University Rennes 1, 35000 Rennes, France., On Behalf Of Société Française de Lutte Contre Les Cancers Et Leucémies de l'Enfant Et de L'adolescent Sfce
Jazyk: angličtina
Zdroj: Cancers [Cancers (Basel)] 2020 Nov 17; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 17.
DOI: 10.3390/cancers12113398
Abstrakt: Data regarding coronavirus disease 2019 (COVID-19) description are still limited in pediatric oncology. The French society of pediatric oncology (SFCE) initiated a study to better describe COVID-19 in patients followed in French pediatric oncology and hematology wards. All patients diagnosed with COVID-19 and followed in a SFCE center were enrolled. Data from medical records were analyzed for all patients enrolled up to the end of May 2020. Data were available for 37 patients. Thirty-one were children under 18 years of age. Nineteen patients were female. Seventeen patients had a solid tumor, 16 had a hematological malignancy and four recently underwent hematopoietic stem cell transplantation (HSCT) for non-oncological conditions. Twenty-eight patients presented symptoms, most often with fever, cough, rhinorrhea and asthenia. Ground-glass opacities were the most frequent radiological finding with abnormalities mostly bilateral and peripherally distributed. Twenty-four patients received chemotherapy a month prior to COVID-19 diagnosis. Most patients did not require hospitalization. Three patients required oxygen at the time of diagnosis. In total, five patients were admitted in an intensive care unit because of COVID-19 and one died from the disease. Children and young adults treated for a cancer and/or with a HSCT may be at risk for severe COVID-19 and should be closely monitored.
Databáze: MEDLINE
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