| Autor: |
Andrade-Guel M; Center for Research in Applied Chemistry (CIQA), Saltillo, Coahuila 25294, Mexico., Ávila-Orta CA; Center for Research in Applied Chemistry (CIQA), Saltillo, Coahuila 25294, Mexico., Cadenas-Pliego G; Center for Research in Applied Chemistry (CIQA), Saltillo, Coahuila 25294, Mexico., Cabello-Alvarado CJ; CONACYT Research Fellow-Research and Innovation Consortium of the State of Tlaxcala, Tlaxcala C.P. 90000, Mexico., Pérez-Alvarez M; Center for Research in Applied Chemistry (CIQA), Saltillo, Coahuila 25294, Mexico., Reyes-Rodríguez P; Center for Research in Applied Chemistry (CIQA), Saltillo, Coahuila 25294, Mexico., Inam F; Department of Engineering and Construction, University of East London, London E16 2RD, UK., Cortés-Hernández DA; Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV) Saltillo Unit. Av. Industria Metalúrgica #1062 Parque Industrial Saltillo-Ramos Arizpe, Saltillo 25900, Mexico., Quiñones-Jurado ZV; Faculty of Chemical Sciences, Durango State Juárez University, Durango C.P. 34120, Mexico. |
| Abstrakt: |
High uric acid levels cause different clinic conditions. One of them is hyperuricemia, which leads to kidney damage. A solution for eliminating uric acid in the blood is by hemodialysis, which is performed using nanocomposite membranes. In this work, Nylon 6 nanocomposites were synthesized with modified carbon black (MCB), which were considered candidate materials for hemodialysis membranes. The modification of carbon black was made with citric acid using the variable-frequency ultrasound method. The new MCB was characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), X-ray diffraction (XRD), transmission electron microscopy (TEM), and dispersion tests. Nylon 6/MCB nanocomposites were processed using the ultrasound-assisted melt-extrusion method to improve the dispersion procedure of the nanoparticles. The Nylon 6/MCB nanocomposites were characterized by FTIR, TGA, and differential scanning calorimetry (DSC). These were assessed for the absorption of toxins and hemocompatibility. MBC and nanocomposites showed excellent uric acid removal (78-82%) and hemocompatibility (1.6-1.8%). These results suggest that Nylon 6/MCB nanocomposites with low loading percentages can be used on a large scale without compatibility problems with blood. |
