Incidence and impact of hospital-acquired complications in an internal medicine unit of a reference hospital in Cameroon: a prospective cohort study.

Autor:	Sih C; Department of Internal Medicine, Faculty of Health Sciences, University of Buea, Cameroon.; Health and Human Development (2HD) Research Network, Douala, Cameroon., Mbatchou-Ngahane BH; Department of Internal Medicine, Douala General Hospital, Douala, Cameroon.; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon., Mboue-Djieka Y; Health and Human Development (2HD) Research Network, Douala, Cameroon., Ngueng-Eke MC; Department of Internal Medicine, Faculty of Health Sciences, University of Buea, Cameroon.; Health and Human Development (2HD) Research Network, Douala, Cameroon., Mbarga NT; Health and Human Development (2HD) Research Network, Douala, Cameroon., Verla VS; Department of Internal Medicine, Faculty of Health Sciences, University of Buea, Cameroon., Choukem SP; Department of Internal Medicine, Faculty of Health Sciences, University of Buea, Cameroon.; Health and Human Development (2HD) Research Network, Douala, Cameroon.; Department of Internal Medicine, Douala General Hospital, Douala, Cameroon.; Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.
Jazyk:	angličtina
Zdroj:	Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2021 Jul 01; Vol. 115 (7), pp. 772-778.
DOI:	10.1093/trstmh/traa116
Abstrakt:	Background: Hospital-acquired complications (HACs) contribute to increased morbidity, mortality and hospital costs. However, their burden is often overlooked in resource-limited settings. We sought to determine the incidence, risk factors and effects of HACs on direct medical costs. Methods: This was a prospective cohort study conducted in the Internal Medicine inpatient ward of Douala General Hospital over 3 mo. Patients were examined daily from admission to discharge, transfer or death. Incidence of HACs was calculated and risk factors of HACs were determined using univariate and multivariate regression models. Results: The cumulative incidence rate of HACs in 230 participants was 29.2/1000 patient-days. The incidence rate of infectious and non-infectious complications was 8.4/1000 and 20.9/1000 patient-days, respectively. The most common HAC was constipation (8.3/1000 patient-days). The most common infection was urinary tract infection (3.7/1000 patient-days). HIV infection and length of stay >8 d were significantly associated with the occurrence of HACs. Deep vein thrombosis was associated with the highest direct medical cost. Conclusion: The incidence of HACs is high in our setting and leads to increased length of hospital stays as well as greater direct medical costs. Thus, there is a need for effective preventive strategies. (© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)
Databáze:	MEDLINE
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