Insulin autoimmune syndrome: A rare cause of hypoglycemia.

Autor: Maheshwari TM; Departments of Pathology and Family Medicine, LLH Hospital Al Musaffah, Abudhabi, UAE., Sharma A; Departments of Pathology and Family Medicine, LLH Hospital Al Musaffah, Abudhabi, UAE., Maheshwari BB; Departments of Pathology and Family Medicine, LLH Hospital Al Musaffah, Abudhabi, UAE.
Jazyk: angličtina
Zdroj: Journal of family medicine and primary care [J Family Med Prim Care] 2020 Sep 30; Vol. 9 (9), pp. 5046-5048. Date of Electronic Publication: 2020 Sep 30 (Print Publication: 2020).
DOI: 10.4103/jfmpc.jfmpc_319_20
Abstrakt: Insulin autoimmune syndrome (IAS) is a rare cause of hyperinsulinemic hypoglycemia. It is due to autoantibodies to endogenous insulin in person who has never been sensitized to insulin by injections. IAS is a third leading cause of spontaneous hypoglycemia in Japan and it is increasingly being recognized worldwide in non-Asian population. However, we report a case of IAS in Asian male. A certain class of medication called sulfhydryl compounds have been shown to sometimes cause IAS. Recently a compound called alpha lipoic acid (ALA) has been associated with an increased risk of developing IAS. ALA is sometimes used for dieting purposes. We report a case of 36-year-old Indian male presented with symptoms of dizziness and feeling of hunger with sweating, noted to have low blood sugars on multiple occasions. There is a definite history of ALA compound intake as dietary supplements with multivitamins. Subsequently, he was diagnosed as a case of recurrent hypoglycemia from IAS due to ALA intake and managed accordingly.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2020 Journal of Family Medicine and Primary Care.)
Databáze: MEDLINE
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