Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation.

Autor:	Umfress AC; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States., Mawn LA; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States., Joos KM; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States., Donahue SP; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States., Schmitt AD; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States., Shieh C; Vanderbilt Eye Institut, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN, 37232, United States.
Jazyk:	angličtina
Zdroj:	American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2020 Oct 28; Vol. 20, pp. 100982. Date of Electronic Publication: 2020 Oct 28 (Print Publication: 2020).
DOI:	10.1016/j.ajoc.2020.100982
Abstrakt:	Purpose: To report the surgical management of extensive epibulbar dermoids with autologous oral mucous membrane transplantation. Observations: While rare, extensive dermoids that encroach upon the visual axis carry a poor prognosis. We report the case of a 7-week old premature male infant who presented with large bilateral epibulbar dermoids obscuring the visual axis. He was treated first with sequential bilateral optical iridectomies under the clearest corneal areas, followed several months later by sequential dermoid excision and amniotic membrane transplantation in each eye. He subsequently underwent autologous "simple" oral mucosal epithelial transplantation (SOMET) as well as strabismus surgery. Conclusions and Importance: Here we present the first case, to the best of our knowledge, of the use of SOMET in managing post-operative pseudopterygium following dermoid excision. To our knowledge it is the also the first application of this technique in a young pediatric patient. A good clinical outcome may be achieved with SOMET, which may offer a minimally invasive alternative to other traditional modalities. Competing Interests: Dr. Louise Mawn is a consultant for Horizon Therapeutics, but they did not provide any financial contribution to this work, nor is she a consultant to them for an area of ophthalmology related to this case report The authors certify that they have no conflict of interests to disclose. (© 2020 The Authors. Published by Elsevier Inc.)
Databáze:	MEDLINE
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