Alcohol use disorders in multidrug resistant tuberculosis (MDR-TB) patients and their non-tuberculosis family contacts in Nigeria.
| Autor: | Lasebikan VO; Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria., Ige OM; Department of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | The Pan African medical journal [Pan Afr Med J] 2020 Aug 21; Vol. 36, pp. 321. Date of Electronic Publication: 2020 Aug 21 (Print Publication: 2020). |
| DOI: | 10.11604/pamj.2020.36.321.17118 |
| Abstrakt: | Introduction: the main aim of this study was to determine the prevalence and associated factors of alcohol use disorder (AUD) in patients with Multi-Drug Treatment-Resistant Tuberculosis (MDR-TB) compared with their non-tuberculosis control, and its association with disease pattern and associated medical comorbidities. Methods: MDR-TB patients (128) and their respective caregivers were interviewed in a treatment unit in Nigeria. Diagnosis of AUD was made using the Structured Clinical Interview for DSM-IV Axis I Disorder, information was obtained on the severity of the TB and associated health problems. Results: prevalence of AUD was (21.9%) and was significantly higher among cases than in controls (2.3%), p = 0.006. Severe TB, OR = 3.33 (1.56-6.83), hematological diseases, OR = 2.34 (1.06-4.33) and HIV/AIDS, OR = 3.01 (1.67-7.01) were the strongest predictors of AUD at 95% CI. Conclusion: AUD was highly prevalent in MDR-TB and was associated with certain medical comorbidities and increased severity of the illness. Competing Interests: The authors declare no competing interests. (Copyright: Victor Olufolahan Lasebikan et al.) |
| Databáze: | MEDLINE |
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