Factors associated with hospitalization for ischemic stroke and TIA following an emergency department headache visit.

Autor: Liberman AL; Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States of America. Electronic address: avliberm@Montefiore.org., Lu J; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, United States of America. Electronic address: jenny.lu@einsteinmed.org., Wang C; Department of Biostatistics, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States of America. Electronic address: cuiling.wang@einsteinmed.org., Cheng NT; Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States of America. Electronic address: ncheng@montefiore.org., Moncrieffe K; Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States of America. Electronic address: kmoncrie@montefiore.org., Lipton RB; Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States of America. Electronic address: richard.lipton@einsteinmed.org.
Jazyk: angličtina
Zdroj: The American journal of emergency medicine [Am J Emerg Med] 2021 Aug; Vol. 46, pp. 503-507. Date of Electronic Publication: 2020 Nov 07.
DOI: 10.1016/j.ajem.2020.10.082
Abstrakt: Background: Misdiagnosis of cerebrovascular disease among Emergency Department (ED) patients with headache has been reported. We hypothesized that markers of substandard diagnostic processes would be associated with subsequent ischemic cerebrovascular events among patients discharged from the ED with a headache diagnosis even after adjusting for demographic variables and medical history.
Methods: We conducted a case-control study of adult ED patients diagnosed with a primary headache disorder at Montefiore Medical Center from 9/1/2013-9/1/2018. Cases were defined as patients hospitalized for an ischemic stroke or TIA within 365 days of their index ED visit. Control patients were defined as those who lacked a subsequent hospitalization for cerebrovascular disease. Pre-specified demographic, clinical, and diagnostic process factors were compared between groups; conditional logistic regression was used to assess the separate and joint influence of baseline features on risk of cerebral ischemia.
Results: A total of 93 consecutive headache patients with a subsequent ischemic stroke/TIA hospitalization were matched to 93 controls (n = 186). Cases were older than controls and more likely to have traditional cerebrovascular risk factors. Neurological consultation was obtained more often for cases (13% vs. 4%; P = 0.03), cases were in the ED for longer (6 vs. 5 h, P = 0.03), and more frequently received neuroimaging (80% vs. 48%; P < 0.0001). Rates of neurological examination, documented differential diagnoses, and clear discharge follow up plans were similar between cases and controls. In our conditional logistic regression model, only history of prior stroke/TIA was associated with increased odds of subsequent cerebral ischemia.
Conclusion: Factors associated with diagnostic process failures did not increase the odds of subsequent ischemic stroke/TIA hospitalization following ED headache visit in our study.
Competing Interests: Declaration of Competing Interest ALL is supported by NIH grant K23NS107643. JL has no conflict. CW has no conflict. NTC has no conflict. KM has no conflict. RBL has no conflict.
(Copyright © 2020. Published by Elsevier Inc.)
Databáze: MEDLINE