Diagnostic Impact of Quantitative Dual-Energy Computed Tomography Perfusion Imaging for the Assessment of Subsegmental Pulmonary Embolism.

Autor: Celtikci P; From the Department of Radiology., Hekimoglu K; From the Department of Radiology., Kahraman G; From the Department of Radiology., Bozbas S; Department of Pulmonary Diseases., Gultekin B; Department of Cardiovascular Surgery, Baskent University Faculty of Medicine, Ankara, Turkey., Akay HT; Department of Cardiovascular Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Journal of computer assisted tomography [J Comput Assist Tomogr] 2021 Jan-Feb 01; Vol. 45 (1), pp. 151-156.
DOI: 10.1097/RCT.0000000000001106
Abstrakt: Objective: The aim of this study was to investigate the quantitative differences of dual-energy computed tomography perfusion imaging measurements in subsegmental pulmonary embolism (SSPE), between normal lung parenchyma (NLP) and hypoperfused segments (HPS) with and without thrombus on computed tomography angiography (CTA).
Methods: Lung attenuation, iodine density, and normalized uptake values were measured from HPS and NLP on iodine maps of 43 patients with SSPE. Presence of pulmonary embolism (PE) on CTA was recorded. One-way repeated-measures analysis of variance and Kruskal-Wallis analyses with post hoc comparisons were conducted.
Results: The numbers of HPS with and without SSPE on CTA were 45 (55.6%) and 36 (44.4%), respectively. Lung attenuation of NLP was significantly different from HPS (P < 0.001). Iodine density and normalized uptake values of HPS with PE were significantly lower than those of HPS without PE, which is significantly lower than NLP (P < 0.001).
Conclusions: Subsegmental pulmonary embolism causes HPS on dual-energy computed tomography perfusion imaging, which demonstrates different iodine density and normalized uptake values depending on the presence of thrombus.
Competing Interests: The authors declare no conflict of interest.
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Databáze: MEDLINE