The diagnostic value of magnetic resonance imaging in differentiating benign and malignant pediatric ovarian tumors.

Autor: Janssen CL; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands., Littooij AS; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Fiocco M; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.; Mathematical Institute Leiden University, Leiden, The Netherlands.; Medical Statistics, Biomedical Data Science Department, Leiden University Medical Center, Leiden, The Netherlands., Huige JCB; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., de Krijger RR; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Hulsker CCC; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands., Goverde AJ; Department of Reproductive Medicine and Gynaecology, University Medical Center of Utrecht, Utrecht, The Netherlands., Zsiros J; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands., Mavinkurve-Groothuis AMC; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands. a.m.c.mavinkurve-groothuis@prinsesmaximacentrum.nl.
Jazyk: angličtina
Zdroj: Pediatric radiology [Pediatr Radiol] 2021 Mar; Vol. 51 (3), pp. 427-434. Date of Electronic Publication: 2020 Nov 13.
DOI: 10.1007/s00247-020-04871-2
Abstrakt: Background: The diagnostic workup of ovarian tumors in children and adolescents is challenging because preserving fertility, in addition to oncological safety, is of particular importance in this population. Therefore, a thorough preoperative assessment of ovarian tumors is required.
Objective: To investigate the diagnostic value of MR imaging in differentiating benign from malignant ovarian tumors in children and adolescents.
Materials and Methods: We conducted a retrospective study of all children and adolescents age <18 years who underwent MR imaging of ovarian tumors during 2014-2019 at a pediatric specialty center. Two radiologists reviewed all MR imaging. We used pathology reports to define the histological diagnosis.
Results: We included 30 girls who underwent MR imaging for an ovarian tumor. Signs indicative for malignancy were tumors with a diameter ≥8 cm, with areas of contrast enhancement, irregular margins, extracapsular tumor growth, and ascites. All benign and malignant ovarian tumors were correctly identified by the radiologists.
Conclusion: The diagnostic utility of MR imaging in classifying ovarian tumors in children and adolescents as benign or malignant is promising and might aid in defining the indication for ovarian-sparing versus non-ovarian-sparing surgery. We recommend evaluating these tumors with MR imaging prior to deciding on surgical treatment.
Databáze: MEDLINE
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