Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Autor: Gonçalves TJM; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil. Electronic address: thiagojmg@yahoo.com.br., Gonçalves SEAB; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Guarnieri A; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Risegato RC; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Guimarães MP; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., de Freitas DC; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Razuk-Filho A; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Benedito Junior PB; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil., Parrillo EF; Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2020 Dec; Vol. 40, pp. 110-114. Date of Electronic Publication: 2020 Oct 13.
DOI: 10.1016/j.clnesp.2020.10.008
Abstrakt: Background & Aim: Verify the prevalence of hypovitaminosis D and obesity in elderly patients infected by new coronavirus. The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS).
Methods: A cross-sectional descriptive study composed of elderly (age ≥ 60 years) admitted to the ICU. Were collected demographic (sex, age), anthropometric data, presence of comorbidities (hypertension, diabetes, heart disease, lung, neurological and oncological diseases), severity score in ICU (SAPS III), PaO 2 /FiO 2 ratio, analysis of C-reactive protein (CRP) and serum dosage of 25-hydroxy vitamin D (25 OHD) in the first day of hospitalization to identify elderly with hypovitaminosis D (low values < 30 ng/mL). The diagnosis of obesity in elderly was determined by calculating the body mass index (BMI) ≥ 30 kg/m 2 .
Results: A total of 176 elderly met the inclusion criteria. 54% were elderly men and mean age of 72.9 ± 9.1 years. The median BMI was 30.5 (28.1-33) kg/m 2 with 68.7% having a nutritional diagnosis of obesity and 15.3% had BMI ≥ 35 kg/m 2 . The most prevalent comorbidities were hypertension (72.2%) and diabetes (40.9%). Prevalence of hypovitaminosis D with values of 25 OHD <30 ng/mL, < 20 ng/mL and <10 ng/mL was 93.8%, 65.9% and 21% respectively. The prevalence of hypovitaminosis D (<30 ng/mL) in obese elderly was 94.2%. There was a negative and significant bivariate correlation between BMI and levels of 25 OHD (r = - 0.15; p = 0.04).
Conclusion: Hypovitaminosis D and obesity in elderly have a high prevalence in critically ill patients in ICU infected by the new coronavirus. Laboratory investigation of vitamin D becomes important, especially in obese elderly patients.
Competing Interests: Declaration of competing interest None of the co-authors have direct or indirect, financial or other conflicts of interest related to the subject of our report. There is no conflict of interest regarding sponsorship and financing.
(Copyright © 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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