| Autor: |
Khanna OP; Department of Surgery, Hahnemann University, Philadelphia, Pennsylvania., Son DL, Mazer H, Read J, Nugent D, Cottone R, Heeg M, Rezvan M, Viek N, Friedmann M |
| Jazyk: |
angličtina |
| Zdroj: |
Urology [Urology] 1987 Dec; Vol. 30 (6), pp. 520-8. |
| DOI: |
10.1016/0090-4295(87)90429-8 |
| Abstrakt: |
One hundred sixteen patients with superficial bladder cancers (Stages Ta, T1, and TIS) were evaluated and treated with either intravesical bacillus Calmette-Guerin [Tice strain] (BCG) or doxorubicin hydrochloride (Adriamycin [ADR]), in a multicenter study. One hundred nine of these patients currently have follow-up. Of these, 54 were completely resected and 55 incompletely resected. For complete resections, based on recurrence rates per 100 patient months, both BCG (0.22) and ADR (0.91) worked well, although BCG had a slightly lower recurrence rate. However, for incomplete resections, BCG (0.20) had a markedly lower recurrence rate than ADR (2.52). Eighteen patients failed initial treatment, with either BCG or ADR. All have been placed on long-term therapy schedules. Of the 12 failures who currently have follow-up, 11 (92%) have either partially or completely responded with additional intravesical therapy. No patients in this study have yet required cystectomies. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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