| Autor: |
Silva MO; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, São Luís, MA, Brasil., Oliveira PVV; Universidade Federal do Rio Grande do Norte, Hospital Universitário Onofre Lopes, Natal, RS, Brasil., Vale PHC; Universidade Federal do Rio Grande do Norte, Hospital Universitário Onofre Lopes, Natal, RS, Brasil., Cunha RM; Universidade Federal do Rio Grande do Norte, Hospital Universitário Onofre Lopes, Natal, RS, Brasil., Lages JS; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, São Luís, MA, Brasil., Brito DJA; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, São Luís, MA, Brasil., Salgado Filho N; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, São Luís, MA, Brasil., Guedes FL; Universidade Federal do Rio Grande do Norte, Hospital Universitário Onofre Lopes, Natal, RS, Brasil., Silva GEB; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, Laboratório de Imunofluorescência e Microscopia Eletrônica, São Luís, MA, Brasil., Santos RF; Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, São Luís, MA, Brasil. |
| Abstrakt: |
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE. |
