Severe organising pneumonia following COVID-19.

Autor: Vadász I; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany istvan.vadasz@innere.med.uni-giessen.de.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany., Husain-Syed F; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany., Dorfmüller P; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; Institute of Pathology, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany., Roller FC; Department of Radiology, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany., Tello K; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany., Hecker M; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany., Morty RE; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany.; Department of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Hessen, Germany., Gattenlöhner S; Institute of Pathology, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany., Walmrath HD; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany., Grimminger F; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany., Herold S; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany., Seeger W; Department of Internal Medicine, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Hessen, Germany.; Universities of Giessen and Marburg Lung Center, Giessen, Hessen, Germany.; German Center for Lung Research, Giessen, Hessen, Germany.; The Cardio-Pulmonary Institute, Giessen, Hessen, Germany.; Department of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Hessen, Germany.; Institute for Lung Health, Giessen, Hessen, Germany.
Jazyk: angličtina
Zdroj: Thorax [Thorax] 2021 Feb; Vol. 76 (2), pp. 201-204. Date of Electronic Publication: 2020 Nov 11.
DOI: 10.1136/thoraxjnl-2020-216088
Abstrakt: Various forms of diffuse parenchymal lung disease have been proposed as potential consequences of severe COVID‑19. We describe the clinical, radiological and histological findings of patients with COVID‑19-associated acute respiratory distress syndrome who later developed severe organising pneumonia including longitudinal follow-up. Our findings may have important implications for the therapeutic modalities in the late-phase of severe COVID‑19 and might partially explain why a subgroup of COVID‑19 patients benefits from systemic corticosteroids.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE