Clinical Characteristics and Risk Factors for Death of Hospitalized Patients With COVID-19 in a Community Hospital: A Retrospective Cohort Study.

Autor: Rodriguez-Nava G; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Yanez-Bello MA; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Trelles-Garcia DP; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Chung CW; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Chaudry S; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Khan AS; Department of Internal Medicine, AMITA Health Saint Francis Hospital, Evanston, IL., Friedman HJ; Co-Director, Critical Care Units, AMITA Health Saint Francis Hospital, Evanston, IL.; Clinical Associate Professor of Medicine, University of Illinois College of Medicine, Chicago., Hines DW; Department of Infectious Diseases and Infection Control, AMITA Health Saint Francis Hospital, Evanston, IL.; Metro Infectious Disease Consultants, LLC, Burr Ridge, IL.
Jazyk: angličtina
Zdroj: Mayo Clinic proceedings. Innovations, quality & outcomes [Mayo Clin Proc Innov Qual Outcomes] 2021 Feb; Vol. 5 (1), pp. 1-10. Date of Electronic Publication: 2020 Nov 05.
DOI: 10.1016/j.mayocpiqo.2020.10.007
Abstrakt: Objective: To describe the clinical characteristics, outcomes, and risk factors for death of patients with coronavirus disease 2019 (COVID-19) in a community hospital setting.
Patients and Methods: This single-center retrospective cohort study included 313 adult patients with laboratory-confirmed COVID-19 admitted to a community hospital in Cook County, Illinois, from March 1, 2020, to May 25, 2020. Demographics, medical history, underlying comorbidities, symptoms, signs, laboratory findings, imaging studies, management, and progression to discharge or death data were collected and analyzed.
Results: Of 313 patients, the median age was 68 years (interquartile range, 59.0-78.5 years; range, 19-98 years), 182 (58.1%) were male, 119 (38%) were white, and 194 (62%) were admitted from a long-term care facility (LTCF). As of May 25, 2020, there were 212 (67.7%) survivors identified, whereas 101 (32.3%) nonsurvivors were identified. Multivariable Cox regression analysis showed increasing hazards of inpatient death associated with older age (hazard ratio [HR] 1.02; 95% CI, 1.01-1.04), LTCF residence (HR, 3.23; 95% CI, 1.68-6.20), and quick Sequential Organ Failure Assessment scores (HR, 2.59; 95% CI, 1.78-3.76).
Conclusion: In this single-center retrospective cohort study of 313 adult patients hospitalized with COVID-19 illness in a community hospital in Cook County, Illinois, older patients, LTCF residents, and patients with high quick Sequential Organ Failure Assessment scores were found to have worse clinical outcomes and increased risk of death.
(© 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc.)
Databáze: MEDLINE