Expanding living donor liver transplantation: Report of first US living donor liver transplant chain.

Autor: Braun HJ; Department of Surgery, University of California, San Francisco, California, USA., Torres AM; Division of Transplantation, University of California, San Francisco, California, USA., Louie F; Division of Transplantation, University of California, San Francisco, California, USA., Weinberg SD; Division of Transplantation, University of California, San Francisco, California, USA., Kang SM; Department of Surgery, University of California, San Francisco, California, USA.; Division of Transplantation, University of California, San Francisco, California, USA., Ascher NL; Department of Surgery, University of California, San Francisco, California, USA.; Division of Transplantation, University of California, San Francisco, California, USA., Roberts JP; Department of Surgery, University of California, San Francisco, California, USA.; Division of Transplantation, University of California, San Francisco, California, USA.
Jazyk: angličtina
Zdroj: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2021 Apr; Vol. 21 (4), pp. 1633-1636. Date of Electronic Publication: 2020 Dec 08.
DOI: 10.1111/ajt.16396
Abstrakt: Living donor liver transplantation (LDLT) enjoys widespread use in Asia, but remains limited to a handful of centers in North America and comprises only 5% of liver transplants performed in the United States. In contrast, living donor kidney transplantation is used frequently in the United States, and has evolved to commonly include paired exchanges, particularly for ABO-incompatible pairs. Liver paired exchange (LPE) has been utilized in Asia, and was recently reported in Canada; here we report the first LPE performed in the United States, and the first LPE to be performed on consecutive days. The LPE performed at our institution was initiated by a nondirected donor who enabled the exchange for an ABO-incompatible pair, and the final recipient was selected from our deceased donor waitlist. The exchange was performed over the course of 2 consecutive days, and relied on the use and compliance of a bridge donor. Here, we show that LPE is feasible at centers with significant LDLT experience and affords an opportunity to expand LDLT in cases of ABO incompatibility or when nondirected donors arise. To our knowledge, this represents the first exchange of its kind in the United States.
(© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.)
Databáze: MEDLINE
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