Second outbreak of Trichinella pseudospiralis in Europe: clinical patterns, epidemiological investigation and identification of the etiological agent based on the western blot patterns of the patients' serum.

Autor: Gómez-Morales MA; European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Mazzarello G; Clinica Malattie Infettive, University of Genoa (DISSAL), Genoa, Italy.; Ospedale Policlinico San Martino, Genoa, Italy., Bondi E; Pediatric Infectious Disease Division, IRCCS Gaslini, Genoa, Italy., Arenare L; Public Health Service, Azienda Sanitaria Locale 3, Genoa, Italy., Bisso MC; Veterinary Service, Azienda Sanitaria Locale 3, Genoa, Italy., Ludovisi A; European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Amati M; European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Viscoli C; Clinica Malattie Infettive, University of Genoa (DISSAL), Genoa, Italy.; Ospedale Policlinico San Martino, Genoa, Italy., Castagnola E; Pediatric Infectious Disease Division, IRCCS Gaslini, Genoa, Italy., Orefice G; Veterinary Service, Azienda Sanitaria Locale 3, Genoa, Italy., Magnè F; Clinica Malattie Infettive, University of Genoa (DISSAL), Genoa, Italy.; Ospedale Policlinico San Martino, Genoa, Italy.; Maternal and Childhood Department, San Giacomo Hospital, Novi Ligure, Italy., Pezzotti P; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Pozio E; European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy.; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Jazyk: angličtina
Zdroj: Zoonoses and public health [Zoonoses Public Health] 2021 Feb; Vol. 68 (1), pp. 29-37. Date of Electronic Publication: 2020 Nov 08.
DOI: 10.1111/zph.12761
Abstrakt: Trichinellosis is a zoonotic disease due to the ingestion of raw or undercooked meat from animals infected with the larvae of nematodes belonging to the genus Trichinella. In January-February 2015, an outbreak of trichinellosis occurred in Genoa, Northern Italy. The epidemiological link was traced back to a dinner served at an agritourism farm on 31 December 2014, where a majority of the 52 guests had consumed the 'beef' steak tartare. The source of infection was not traced; however, it was noted that the amount of beef purchased officially for providing at the dinner did not correspond with that served, suggesting that meat of a different origin had been added to the beef to prepare the steak tartare. Clinical and laboratory data of 30 individuals out of the 52 (57.7%), of which four were hospitalized, were consistent with that of the case definition of trichinellosis. Western blot patterns of the sera from patients with confirmed trichinellosis were similar to the diagnostic pattern identified for the reference sera of Trichinella pseudospiralis but different from those of the control sera tested for patients infected with Trichinella spiralis and Trichinella britovi. Identification of T. pseudospiralis as the aetiological agent responsible for the outbreak of trichinellosis using an indirect tool represents an advancement in the epidemiological investigation of this zoonotic disease.
(© 2020 The Authors. Zoonoses and Public Health published by Wiley-VCH GmbH.)
Databáze: MEDLINE
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