Widespread Traces of Lytic Kaposi Sarcoma-Associated Herpesvirus in Primary Effusion Lymphoma at Single-Cell Resolution.
| Autor: | Rondeau NC; Department of Biology, Barnard College, Columbia University, New York, New York, USA., Finlayson MO; JP Sulzberger Columbia Genome Center, Columbia University Irving Medical Center, New York, New York, USA., Miranda JL; Department of Biology, Barnard College, Columbia University, New York, New York, USA jj@jjmirandalab.org. |
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| Jazyk: | angličtina |
| Zdroj: | Microbiology resource announcements [Microbiol Resour Announc] 2020 Nov 05; Vol. 9 (45). Date of Electronic Publication: 2020 Nov 05. |
| DOI: | 10.1128/MRA.00851-20 |
| Abstrakt: | Cancer cells of primary effusion lymphoma (PEL) often contain both Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). We measured the interplay of human, KSHV, and EBV transcription in a cell culture model of PEL using single-cell RNA sequencing. The data detect widespread trace expression of lytic KSHV genes. (Copyright © 2020 Rondeau et al.) |
| Databáze: | MEDLINE |
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