A Case-Control Study to Evaluate Candidal Parameters in the Oral Cavity of Patients with Type 2 Diabetes Mellitus.
| Autor: | Vijayalakshmi L; Department of Oral Medicine and Radiology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India., Raj JBS; Department of Oral Medicine and Radiology, Vivekananda Dental College for Women, Thiruchengode, Tamil Nadu, India., Kavitha J; Department of Periodontology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India., Krishnaraj S; Department of Periodontology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India., Manovijay B; Department of Periodontology, Vinayaka Mission Sankarachariar Dental College, Salem, Tamil Nadu, India., Manikandan D; Department of Periodontology, CSI College of Dental Sciences, Madurai, Tamil Nadu, India. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2020 Aug; Vol. 12 (Suppl 1), pp. S389-S393. Date of Electronic Publication: 2020 Aug 28. |
| DOI: | 10.4103/jpbs.JPBS_115_20 |
| Abstrakt: | Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM). Materials and Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study. The χ2 test was used to examine the characteristics of the samples. Results: The results found that there is a significant difference in saliva and swab for Candida growth between patients with type 2 DM and normal healthy individuals. Swab had shown slightly more Candida growth than saliva in group A (type 2 DM). No significant variation in Candida growth was found. Candida krusei was seen in normal healthy individuals alone. In antifungal susceptibility pattern to various antifungal agents, Candida tropicalis has shown a significant result for various antifungal agents whereas Candida albicans and Candida dubliniensis did not show any significant result for various antifungal agents used in group A (patients with type 2 DM). Conclusion: Diabetic individuals who are prone to a hyperglycemic state favors the growth and establishment of Candida species. Although a smaller percentage of multidrug-resistant Candida species has been observed in the saliva of patients with type 2 DM. Competing Interests: There are no conflicts of interest. (Copyright: © 2020 Journal of Pharmacy and Bioallied Sciences.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|