Extracavitary primary effusion lymphoma recurring with syphilis in an HIV-infected patient.
| Autor: | Sohail Ahmed D; Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Hematology and Chronic Viral Illness Service, McGill University Health Centre, Montreal, Quebec, Canada., Poliquin M; Clinique médicale L' Agora, Montreal, Quebec, Canada., Julien LA; Department of Pathology, McGill University Health Centre, Montreal, Quebec, Canada., Routy JP; Department of Medicine, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada jean-pierre.routy@mcgill.ca.; Division of Haematology, McGill University Health Centre, Montreal, Quebec, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2020 Nov 04; Vol. 13 (11). Date of Electronic Publication: 2020 Nov 04. |
| DOI: | 10.1136/bcr-2020-235204 |
| Abstrakt: | A 59-year-old Caucasian man infected with HIV, in remission from human herpes virus-8-positive extracavitary primary effusion lymphoma (EC-PEL), presented to a sexual health clinic with fever and rectal pain 10 weeks after a single episode of receptive anal sexual intercourse with another man. He was initially treated for a presumptive diagnosis of lymphogranuloma venereum proctitis, then for syphilis on positive serology. Rectosigmoidoscopy revealed a single ulcerated rectal mass; endoscopic biopsies confirmed the recurrence of EC-PEL. The patient received chemotherapy and went into remission. This is the first reported case of EC-PEL occurring synchronously with early syphilis, and specifically at the site of inoculation, which can be a major diagnostic challenge since both conditions may present with lymphadenopathy, mucosal involvement and constitutional symptoms. We reviewed the literature for similar cases and hypothesised that syphilis may have triggered the recurrence of this rare lymphoma. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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