The experience of the health care workers of a severely hit SARS-CoV-2 referral Hospital in Italy: incidence, clinical course and modifiable risk factors for COVID-19 infection.

Autor:	Colaneri M; Division of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Novelli V; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Cutti S; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Muzzi A; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Resani G; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Public Health, Experimental and Forensic Medicine, Section of Hygiene, University of Pavia, Pavia, Italy., Monti MC; Department of Public Health, Experimental and Forensic Medicine, Unit of Biostatistics and Clinical Epidemiology, University of Pavia, Pavia, Italy., Rona C; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Grugnetti AM; Department of Health Professions, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Rettani M; Information Tecnology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Rovida F; Department of Microbiology and Virology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Zuccaro V; Division of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Triarico A; Department of Hospital Leadership, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Marena C; Medical Direction, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Jazyk:	angličtina
Zdroj:	Journal of public health (Oxford, England) [J Public Health (Oxf)] 2021 Apr 12; Vol. 43 (1), pp. 26-34.
DOI:	10.1093/pubmed/fdaa195
Abstrakt:	Background: During the COVID-19 pandemic, the health care workers (HCWs) at the frontline have been largely exposed to infected patients, running a high risk of being infected by the SARS-CoV-2 virus.Since limiting transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in health care setting is crucial to avoid the community spread of SARS-CoV-2, we want to share our experience as an early hit hospital where standard infection control practices have been conscientiously applied and effective. We believe that our example, as first and hardest hit country, might be a warning and aid not only for those who have been hit later, but also for a second fearful wave of contagion. In addition, we want to offer an insight on modifiable risk factors for HWs-related infection. Methods: Demographic, lifestyle, work-related and comorbidities data of 1447 HCWs, which underwent a nasopharyngeal swab for SARS-CoV-2, were retrospectively collected. For the 164 HCWs positive for SARS-CoV-2, data about safety in the workplace, symptoms and clinical course of COVID-19 were also collected. Cumulative incidence of SARS-CoV-2 infection was estimated. Risk factors for SARS-CoV-2 infection were assessed using a multivariable Poisson regression. Results: The cumulative incidence of SARS-CoV-2 infection among the screened HCWs was 11.33% (9.72-13.21). Working in a COVID-19 ward, being a former smoker (versus being a person who never smoked) and BMI was positively associated with SARS-CoV-2 infection, whereas being a current smoker was negatively associated with this variable. Conclusions: Assuming an equal accessibility and proper use of personal protective equipment of all the HCWs of our Hospital, the great and more prolonged contact with COVID-19 patients remains the crucial risk factor for SARS-CoV-2. Therefore, increased and particular care needs to be focused specifically on the most exposed HCWs groups, which should be safeguarded. Furthermore, in order to limit the risk of asymptomatic spread of SARS-CoV-2 infection, the HCWs mild symptoms of COVID-19 should be considered when evaluating the potential benefits of universal staff testing. (© The Author(s) 2020. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
Databáze:	MEDLINE
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