Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients. A single-center experience.
| Autor: | Naeem KB; Ministry of Health and Prevention, Mohammed bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates. E-mail. kbncardiology@yahoo.co.uk., Hachim MY, Hachim IY, Chkhis A, Quadros R, Hannawi H, Al Salmi I, Alokaily F, Hannawi S |
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| Jazyk: | angličtina |
| Zdroj: | Saudi medical journal [Saudi Med J] 2020 Nov; Vol. 41 (11), pp. 1204-1210. |
| DOI: | 10.15537/smj.2020.11.25466 |
| Abstrakt: | Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population. Methods: A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury. Results: During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death. Conclusion: Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multi-organ damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended. |
| Databáze: | MEDLINE |
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