Comparison of PPI and combined treatment in the treatment of recurrent laryngeal contact granuloma.

Autor: Nie Q; Anhui Medical University, Hefei, China; Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Medical Center of PLA General Hospital, Beijing, China., Li J; Anhui Medical University, Hefei, China; Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Medical Center of PLA General Hospital, Beijing, China. Electronic address: entljr@sina.com., Zou S; Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Medical Center of PLA General Hospital, Beijing, China., Zhang R; Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Jazyk: angličtina
Zdroj: American journal of otolaryngology [Am J Otolaryngol] 2021 Jan - Feb; Vol. 42 (1), pp. 102766. Date of Electronic Publication: 2020 Oct 22.
DOI: 10.1016/j.amjoto.2020.102766
Abstrakt: Objective: To compare the therapeutic effect of PPI and combined treatment in the treatment of patients with recurrent laryngeal contact granuloma.
Methods: The clinical data of 299 patients with recurrent laryngeal contact granuloma treated with PPI or combined treatment (PPI with glucocorticoid injection into granuloma by the thyroglossal approach) from February 2013 to June 2019 were analyzed retrospectively. Patients were divided into two subgroups: PPI and combined treatment. The cure rates, recurrence rates and cure time of the two subgroups were compared and analyzed separately. Than we can get the optimal treatment of the two treatment in the treatment of recurrent patients.
Results: In recurrent patients, the cure rate (81.20%) and recurrence rate (3%) of combined treatment were superior to those of PPI (57.58%) and recurrence rate (12.12%); (P < 0.05). The cure time of PPI was longer than that of combination therapy (P < 0.001).
Conclusion: The therapeutic effect of combined treatment is better than that of PPI in patients with recurrence. At the same time, combined treatment is an effective treatment for recurrent granuloma and can be used as a first-line treatment for recurrent laryngeal contact granuloma.
(Copyright © 2020 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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