Four in one: Four recepients with a single donor tissue - A novel concept for eye transplantation surgery post-COVID-19.

Autor: Siddharthan KS; Head-Cornea Services, Sankara Eye Hospital, Coimbatore, India., Agrawal A; Fellow, Cornea Services, Sankara Eye Hospital, Coimbatore, India., Reddy JK; Director, Technical, Sankara Eye Hospital, Coimbatore, India.
Jazyk: angličtina
Zdroj: Indian journal of ophthalmology [Indian J Ophthalmol] 2020 Nov; Vol. 68 (11), pp. 2471-2474.
DOI: 10.4103/ijo.IJO_1602_20
Abstrakt: A donor corneo-scleral button was dissected into four parts using a simple manual technique. The anterior corneal lamellae was stripped from the Descemet's Membrane (DM) and Deep Anterior Lamellar Keratoplasty (DALK) was performed in a patient with advanced keratoconus after removing the recipient's stroma using the big bubble technique. Descemet's Membrane Endothelial Keratoplasty (DMEK) was done with the stripped donor DM in a patient with Fuch's endothelial dystroph (FECD). The cadaveric limbal stem cells from the tissue were used for simple limbal epithelial transplantation (SLET) in a Steven- Johnson Syndrome (SJS) with localized limbal stem deficiency and symblepharon. The sclera was used to revise a leaking hypotonus bleb in an advanced single-eyed glaucoma patient. No intraoperative or postoperative complications were observed. At 1 year, all the 4 cases retained healthy transplanted tissues with good visual outcomes. Shortage of donor eyes is a global problem and with the present COVID-19 scenario the situation is bound to worsen. The advent of customized component corneal transplantation using simple cost-effective techniques will be the future trend in the years to come.
Competing Interests: None
Databáze: MEDLINE
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