The effect of simultaneous dual-focus integration on the global flash multifocal electroretinogram in the human eye.

Autor: Fung MMY; The Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China., Choi KY; The Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.; Laboratory of Experimental Optometry (Neuroscience), School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China., Chan HHL; The Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.; Laboratory of Experimental Optometry (Neuroscience), School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.; Centre for Eye and Vision Research, Hong Kong, China.
Jazyk: angličtina
Zdroj: Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) [Ophthalmic Physiol Opt] 2021 Jan; Vol. 41 (1), pp. 171-178. Date of Electronic Publication: 2020 Oct 29.
DOI: 10.1111/opo.12751
Abstrakt: Purpose: To investigate the effect of simultaneous dual-focus (DF) on retinal activities measured by global flash multifocal electroretinogram (mfERG).
Methods: Thirty adults were recruited for mfERG measurement under three conditions: in-focus (i.e., no defocus), +2.50 D DF and +7.50 D DF, administered using single vision contact lenses and DF lenses. The direct component (DC) and the induced component (IC) of the mfERG were pooled into central macular (0-8°), para-macular (8-18°) and peri-macular (18-30°) regions, and then compared across the three conditions using two-way, repeated measures ANOVA.
Results: Simultaneous DF had a significant effect on the IC amplitude, which was significantly stronger under +7.50 D DF (p < 0.01) than for the in-focus condition, which was mostly derived from the central and para-macular regions. No significant effect was observed for the +2.50 D DF condition.
Conclusion: Under the effect of relatively strong simultaneous DF integration, the retina showed an enhanced retinal response, which originated from the inner retina. Compared with the peri-macular region, central and para-macular responses appeared to be enhanced.
(© 2020 The Authors Ophthalmic and Physiological Optics © 2020 The College of Optometrists.)
Databáze: MEDLINE
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