The Prevalence and Predictors of Non-alcoholic Fatty Liver Disease in Morbidly Obese Women - A Cross-sectional Study from Southern India.

Autor:	Atri A; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Jiwanmall SA; Department of Psychiatry, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Nandyal MB; Department of Psychiatry, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Kattula D; Department of Psychiatry, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Paravathareddy S; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Paul TV; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Thomas N; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Kapoor N; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.; Noncommunicable Disease Unit, Melbourne School of Population and Global Health, University of Melbourne, Victoria, Australia.
Jazyk:	angličtina
Zdroj:	European endocrinology [Eur Endocrinol] 2020 Oct; Vol. 16 (2), pp. 152-155. Date of Electronic Publication: 2020 Oct 06.
DOI:	10.17925/EE.2020.16.2.152
Abstrakt:	Background: The prevalence of obesity is increasing rapidly in India and so are its associated comorbidities. Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome, is commonly associated with obesity. However, limited data are available on its prevalence and clinical indicators among morbidly obese Indian women. The aim of our study was to find the prevalence of NAFLD in morbidly obese Indian women and study the clinically measurable obesity indicators that would best predict NAFLD. Methods: This was a cross-sectional study, conducted in the Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore. Women were enrolled who were diagnosed to have NAFLD on sonography. Anthropometric variables, such as body mass index, waist circumference, hip circumference, waist-hip ratio and waist-height ratio were measured and compared between the two groups. SPSS Statistics 21.0 software was used for analysing the data. Results: One hundred and six consecutive, morbidly obese women were recruited in this study. Nearly three-quarters (73.6%) of the 106 morbidly obese participants were found to have NAFLD. We found waist circumference, body mass index and waist-height ratio to be most useful in distinguishing between patients with and without NAFLD, and found waist-height ratio was the best screening tool for diagnosing NAFLD. Conclusion: NAFLD is present in a large proportion of morbidly obese women. Waist-height ratio could be used a surrogate screening tool to detect NAFLD in resource-constrained settings. Competing Interests: Disclosures: Avica Atri, Stephen A Jiwanmall, Munaf B Nandyal, Dheeraj Kattula, Sandhiya Paravathareddy, Thomas V Paul, Nihal Thomas and Nitin Kapoor have no financial or non-financial relationships or activities to declare in relation to this article. (© Touch Medical Media 2020.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu