Onchocerciasis Elimination: Progress and Challenges.
| Autor: | Lakwo T; Neglected Tropical Disease Control Program, Vector Control Division, Ministry of Health, Kampala, Uganda., Oguttu D; Neglected Tropical Disease Control Program, Vector Control Division, Ministry of Health, Kampala, Uganda., Ukety T; Centre de Recherche pour les Maladies Tropicales, Rethy, Ituri Province, The Democratic Republic of the Congo., Post R; Disease Control Department, London School of Hygiene & Tropical Medicine, London, UK.; School of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK., Bakajika D; Expanded Special Project for Elimination of Neglected Tropical Diseases, WHO Regional Office for Africa, Brazzaville, Congo. |
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| Jazyk: | angličtina |
| Zdroj: | Research and reports in tropical medicine [Res Rep Trop Med] 2020 Oct 07; Vol. 11, pp. 81-95. Date of Electronic Publication: 2020 Oct 07 (Print Publication: 2020). |
| DOI: | 10.2147/RRTM.S224364 |
| Abstrakt: | Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus and transmitted through the bites of black flies of the genus Similium that breed in rivers and streams. The impact of mass treatment with ivermectin and supplemented by vector control in some countries has changed the global scene of onchocerciasis. There has been reported progress made in elimination of onchocerciasis in central and southern American countries and in some localities in Africa. The target for elimination in the Americas has been set at 2022 while for 12 countries in Africa this is expected in 2030. This review was conducted to examine the current status of onchocerciasis elimination at the global level and report on progress made. Literature searches were made through PubMed, articles in English or English abstracts, reports and any other relevant articles related to the subject. The global burden of onchocerciasis is progressively reducing and is no longer a public health problem in some regions. However, programs are challenged with a range of issues: cross-border transmission, diagnostic tools, Loa loa co-endemicity, limited workforce in entomology and maintaining enthusiasm among community drug distributors. More concerted effort using appropriate tools is required to overcome the challenges. Competing Interests: Rory Post reports personal fees from Sightsavers, The Carter Center, and The End Fund, outside the submitted work. The authors report no other potential conflicts of interest for this work. (© 2020 Lakwo et al.) |
| Databáze: | MEDLINE |
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