Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.

Autor: Hartmann FE; Ecologie Systematique Evolution, Batiment 360, Université Paris-Saclay, CNRS, AgroParisTech, Orsay, 91400, France., Duhamel M; Ecologie Systematique Evolution, Batiment 360, Université Paris-Saclay, CNRS, AgroParisTech, Orsay, 91400, France.; Ruhr-Universität Bochum, Evolution of Plants and Fungi - Gebäude ND 03/174, Universitätsstraße, 150, 44801 Bochum, Germany., Carpentier F; Ecologie Systematique Evolution, Batiment 360, Université Paris-Saclay, CNRS, AgroParisTech, Orsay, 91400, France., Hood ME; Biology Department, Science Centre, Amherst College, Amherst, MA, 01002, USA., Foulongne-Oriol M; Mycologie et Sécurité des Aliments, MycSA, INRAE, Villenave d'Ornon, 33882, France., Silar P; Lab Interdisciplinaire Energies Demain, Univ Paris Diderot, Sorbonne Paris Cite, Paris 13, F-75205, France., Malagnac F; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, 91198, France., Grognet P; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, 91198, France., Giraud T; Ecologie Systematique Evolution, Batiment 360, Université Paris-Saclay, CNRS, AgroParisTech, Orsay, 91400, France.
Jazyk: angličtina
Zdroj: The New phytologist [New Phytol] 2021 Mar; Vol. 229 (5), pp. 2470-2491. Date of Electronic Publication: 2020 Dec 01.
DOI: 10.1111/nph.17039
Abstrakt: Genomic regions determining sexual compatibility often display recombination suppression, as occurs in sex chromosomes, plant self-incompatibility loci and fungal mating-type loci. Regions lacking recombination can extend beyond the genes determining sexes or mating types, by several successive steps of recombination suppression. Here we review the evidence for recombination suppression around mating-type loci in fungi, sometimes encompassing vast regions of the mating-type chromosomes. The suppression of recombination at mating-type loci in fungi has long been recognized and maintains the multiallelic combinations required for correct compatibility determination. We review more recent evidence for expansions of recombination suppression beyond mating-type genes in fungi ('evolutionary strata'), which have been little studied and may be more pervasive than commonly thought. We discuss testable hypotheses for the ultimate (evolutionary) and proximate (mechanistic) causes for such expansions of recombination suppression, including (1) antagonistic selection, (2) association of additional functions to mating-type, such as uniparental mitochondria inheritance, (3) accumulation in the margin of nonrecombining regions of various factors, including deleterious mutations or transposable elements resulting from relaxed selection, or neutral rearrangements resulting from genetic drift. The study of recombination suppression in fungi could thus contribute to our understanding of recombination suppression expansion across a broader range of organisms.
(© 2020 The Authors New Phytologist © 2020 New Phytologist Foundation.)
Databáze: MEDLINE
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