Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis.
Autor: | Sasikumar PK; Department of Periodontics, JKKN Dental College, Namakkal, Tamil Nadu, India., Varghese SS; Department of Periodontics, Saveetha Dental College, Chennai, Tamil Nadu, India., Kumaran T; Department of Periodontics, JKKNDCH, Thiruchengodu, Tamil Nadu, India., Devi SS; Department of Oral Medicine Andradiology, KSR Institute of Dental Science and Research, Thiruchengodu, Tamil Nadu, India. |
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Jazyk: | angličtina |
Zdroj: | Contemporary clinical dentistry [Contemp Clin Dent] 2020 Jan-Mar; Vol. 11 (1), pp. 3-9. Date of Electronic Publication: 2020 Jul 13. |
DOI: | 10.4103/ccd.ccd_448_19 |
Abstrakt: | The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis. Competing Interests: There are no conflicts of interest. (Copyright: © 2020 Contemporary Clinical Dentistry.) |
Databáze: | MEDLINE |
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